Mouse Anti-Atg8 Antibody (MOFAB-740W)


Cat: MOFAB-740W
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Lot Number

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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MOFAB-740W Monoclonal WB, IHC, IF 100 µg
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CBMOAB-00395CR Monoclonal Yeast WB, ELISA MO00395CR 100 µg
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MO-DKB-0063RA Polyclonal IL, WB 50 µL
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MO-DKB-03765W Polyclonal Yeast ELISA, WB, IHC, IP 100 µg
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Specifications

Host speciesMouse
Species ReactivityYeast, A. thaliana (Arabidopsis thaliana); A. madagascariensis (Adansonia madagascariensis); C. reinhardtii (Chlamydomonas reinhardtii); N. benthamiana (Nicotiana benthamiana); P. trichocarpa (Populus trichocarpa); S. lycopersicum (Solanum lycopersicum)
ImmunogenAtg8 Antibody detects endogenous levels of total Atg8.
FormatLiquid or Lyophilized
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB, IHC, IF
Application NotesWB: 1:1000-1:2000
IHC/IF: 1:100-1:1000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionUbiquitin-like modifiers are involved in autophagosome formation. Mediates autophagosome delivery to vacuoles through the microtubule cytoskeleton using ATG4. Selective autophagic degradation of the nucleus (nucleophagy) and required for mitophagy, which helps to regulate mitochondrial quantity and quality by eliminating mitochondria to basal levels to meet cellular energy demands and prevent excess ROS production. Also involved in membrane fusion events that occur in the early secretory pathway. It is also involved in the endoplasmic reticulum-specific autophagy process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, resulting in the expansion of the autophagosome membrane during autophagy.
Product OverviewThis product is a Mouse antibody against the Atg8. It can be used for Atg8 antibody detection in Western Blot, Immunohistochemistry, Immunofluorescence.
Alternative NamesAutophagy-related protein 8; Autophagy-related ubiquitin-like modifier ATG8; Pexophagy zeocin-resistant mutant protein 2; PAZ2;
UniProt IDQ8NJJ4
For Research Use Only | Not For Clinical Use.
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