Beclin 1-associated autophagy-related key regulator
Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).
Mouse Anti-Atg14 Antibody (CBMOAB-01989FYA) (CAT#: CBMOAB-01989FYA)
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- Host species: Mouse
- Species Reactivity: Fruit fly (Drosophila melanogaster), Marmoset
- Application: WB, ELISA
- Protein: Submitted name: Autophagy-related 14
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: CG11877, LD37690p, Atg14
Mouse Anti-ATG14 Antibody (CBMOAB-00371CR) (CAT#: CBMOAB-00371CR)
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- Host species: Mouse
- Species Reactivity: Yeast, Marmoset
- Application: WB, ELISA
- Protein: Autophagy-related protein 14
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Autophagy-related protein 14, Cytoplasm to vacuole targeting protein 12, ATG14, APG14 CVT12, YBR128C
Mouse Anti-ATG14 Antibody (MO-AB-13738W) (CAT#: MO-AB-13738W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes), Marmoset
- Application: WB, ELISA
- Protein: Submitted name: ATG14 autophagy related 14 homolog
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: ATG14 autophagy related 14 homolog, ATG14
