BRCA1 Associated RING Domain 1
This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Mouse Anti-Arabidopsis BARD1 Antibody (CBMOAB-25066FYC) (CAT#: CBMOAB-25066FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: BRCA1-associated RING domain protein 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: BRCA1 Associated RING Domain 1, RING-Type E3 Ubiquitin Transferase BARD1, EC 2.3.2.27, BARD-1
Mouse Anti-Rhesus BARD1 Antibody (CBMOAB-36774FYA) (CAT#: CBMOAB-36774FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: BRCA1 associated RING domain 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: BARD1
Mouse Anti-Cattle BARD1 Antibody (MO-AB-07968R) (CAT#: MO-AB-07968R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: WB, ELISA
- Protein: Submitted name: BARD1 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: BARD1 protein, Fragment, BARD1
Mouse Anti-Chimpanzee BARD1 Antibody (MO-AB-21326W) (CAT#: MO-AB-21326W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Submitted name: BRCA1 associated RING domain 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: BRCA1 associated RING domain 1, BARD1
Rabbit Anti-BARD1 Antibody (MO-DKB-02312W) (CAT#: MO-DKB-02312W)
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- Host species: Rabbit
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, Co-IP
- Protein: Submitted name: Breast cancer associated RING 1
- Size: 150µg
- Conjugate: NONE
- Alternative Names: BRCA1 Associated RING Domain 1, RING-Type E3 Ubiquitin Transferase BARD1, EC 2.3.2.27, BARD-1, BARD1, ATBARD1, BREAST CANCER ASSOCIATED RING 1, REPRESSOR OF WUSCHEL1, ROW1
Mouse Anti-Zebrafish bard1 Antibody (CBMOAB-67436FYA) (CAT#: CBMOAB-67436FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: BRCA1-associated RING domain 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: bard1, BRCA1 Associated RING Domain 1
Mouse Anti-Frog bard1 Antibody (MO-AB-01803H) (CAT#: MO-AB-01803H)
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- Host species: Mouse
- Species Reactivity: Frog (Xenopus laevis)
- Application: WB, ELISA
- Protein: Submitted name: BRCA1-associated RING domain protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: BRCA1-associated RING domain protein, bard1, BARD1
