Caspase 3
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Mouse Anti-CASP3 Antibody (CBMOAB-25710FYC) (CAT#: CBMOAB-25710FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Goat (Capra hircus), Hamsters (Cricetinae), Horse (Equus caballus), Human, Mouse, Rat, Rabbit, Chicken, Guinea Pig, Hamster, Monkey, Sheep, Bovine, Canine, Porcine, Yeast, O. mykiss (Oncorhynchus mykiss), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish
- Application: WB, ELISA
- Protein: Casparian strip membrane protein 3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: Caspase 3, Caspase 3, Apoptosis-Related Cysteine Peptidase, Caspase 3, Apoptosis-Related Cysteine Protease, SREBP Cleavage Activity 1, Cysteine Protease CPP32, Protein Yama, EC 3.4.22.56, Apopain, CASP-3
For Research Use Only | Not For Clinical Use.