Histidine-rich glycoprotein

Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions. Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes. Binds T-cells and alters the cell morphology Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2 (By similarity). Tethers plasminogen to the cell surface.

  • Mouse Anti-D. melanogaster Hrg Antibody (CBMOAB-20763FYA) (CAT#: CBMOAB-20763FYA)

    • Host species: Mouse
    • Species Reactivity: Fruit fly (Drosophila melanogaster)
    • Application: WB, ELISA
    • Protein: Poly(A) polymerase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: FI03258p, Hiiragi, isoform A, EC 2.7.7.19, Hiiragi, isoform B, EC 2.7.7.19, Hiiragi, isoform C, EC 2.7.7.19, Poly A polymerase, RE09914p, hrg, hrg-RA PAP
  • Mouse Anti-Rhesus HRG Antibody (CBMOAB-44819FYA) (CAT#: CBMOAB-44819FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Histidine rich glycoprotein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: HRG
  • Mouse Anti-Rabbit HRG Antibody (MO-AB-08397Y) (CAT#: MO-AB-08397Y)

    • Host species: Mouse
    • Species Reactivity: Rabbit (Oryctolagus cuniculus)
    • Application: WB, ELISA
    • Protein: Submitted name: Histidine-rich glycoprotein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Histidine-rich glycoprotein, HRG
  • Mouse Anti-Cattle HRG Antibody (MO-AB-13804R) (CAT#: MO-AB-13804R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Submitted name: Histidine-rich glycoprotein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Histidine-rich glycoprotein, HRG
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