Prohormone convertase 1

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

  • Mouse Anti-Rhesus PCSK1 Antibody (CBMOAB-54056FYA) (CAT#: CBMOAB-54056FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Neuroendocrine convertase 1 isoform 1 preproprotein, PCSK1
  • Mouse Anti-Chimpanzee PCSK1 Antibody (MO-AB-16741W) (CAT#: MO-AB-16741W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Proprotein convertase subtilisin / kexin type 1, PCSK1
  • Mouse Anti-Cattle PCSK1 Antibody (MO-AB-17640R) (CAT#: MO-AB-17640R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Neuroendocrine convertase 1, NEC 1, EC 3.4.21.93, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1
  • Mouse Anti-Pig PCSK1 Antibody (MO-AB-28163R) (CAT#: MO-AB-28163R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Proprotein convertase subtilisin/kexin type 1, Fragment, PCSK1
  • Mouse Anti-Goat PCSK1 Antibody (MO-AB-37936W) (CAT#: MO-AB-37936W)

    • Host species: Mouse
    • Species Reactivity: Goat (Capra hircus)
    • Application: WB, ELISA
    • Protein: Submitted name: Proprotein convertase subtilisin/kexin type 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Proprotein convertase subtilisin / kexin type 1, PCSK1
  • Mouse Anti-Marmoset PCSK1 Antibody (MO-AB-61144W) (CAT#: MO-AB-61144W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Neuroendocrine convertase 1 isoform 1 preproprotein, PCSK1
  • Rabbit Anti-PCSK1 (Center) Antibody (Cat MO-DKB-03375W) (CAT#: MO-DKB-03375W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Zebrafish (Danio rerio)
    • Application: WB, IHC, IHC-P
    • Protein: Neuroendocrine convertase 1
    • Size: 100µL
    • Conjugate: Unconjugated
    • Alternative Names: Prohormone convertase 1, pcsk
  • Mouse Anti-Zebrafish pcsk1 Antibody (CBMOAB-91898FYA) (CAT#: CBMOAB-91898FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Neuroendocrine convertase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Prohormone convertase 1, pcsk
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