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Protein tyrosine phosphatase, receptor type, C

Protein tyrosine phosphatase, receptor type, C, also known as PTPRC, is an enzyme encoded by the PTPRC gene in humans. PTPRC is also called CD45 antigen (CD stands for differentiation cluster) and was originally called Leukocyte Common Antigen (LCA).

The protein product of this gene, most famously CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTP is a signaling molecule that regulates various cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

CD45 is a type I transmembrane protein and exists in various isoforms in all differentiated hematopoietic cells (except red blood cells and plasma cells). CD45 has been shown to be an important regulator of T cell and B cell antigen receptor signal transduction. It plays a role by directly interacting with the components of the antigen receptor complex through its extracellular domain (a form of co-stimulation), or through its cytoplasmic domain to activate various Src family kinases required for antigen receptor signal transduction. CD45 can also inhibit JAK kinase, so it can be used as a negative regulator of cytokine receptor signal transduction.

Cat# Product Name Host species Species Reactivity Application Size Conjugate Alternative Names Protein
CBMOAB-00049FYA Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00049FYA) Mouse Cattle (Bos taurus) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00050FYA Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00050FYA) Mouse Cattle (Bos taurus) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00051FYA Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00051FYA) Mouse Cattle (Bos taurus) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00052FYA Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00052FYA) Mouse Cattle (Bos taurus) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00136FYA Mouse Anti-Dog PTPRC Antibody (CBMOAB-00136FYA) Mouse Dog (Canis lupus familiaris) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00180FYA Mouse Anti-Rabbit PTPRC Antibody (CBMOAB-00180FYA) Mouse Rabbit (Oryctolagus cuniculus) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
CBMOAB-00218FYA Mouse Anti-Alpaca PTPRC Antibody (CBMOAB-00218FYA) Mouse Alpaca (Vicugna pacos), Llama (camel) FC 100µg None B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
MO-AB-05414W Mouse Anti-Rhesus PTPRC Antibody (MO-AB-05414W) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Receptor-type tyrosine-protein phosphatase C isoform 1, PTPRC Submitted name: Receptor-type tyrosine-protein phosphatase C isoform 1
MO-AB-05415W Mouse Anti-Rhesus PTPRC Antibody (MO-AB-05415W) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200 Protein-tyrosine-phosphatase
MO-AB-09789W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-09789W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-09896W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-09896W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-10235W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-10235W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-18836R Mouse Anti-Cattle PTPRC Antibody (MO-AB-18836R) Mouse Cattle (Bos taurus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP PTPRC protein, Fragment, PTPRC Protein-tyrosine-phosphatase
MO-AB-25498W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-25498W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Protein tyrosine phosphatase, receptor type, C, PTPRC Protein-tyrosine-phosphatase
MO-AB-26853W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-26853W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-27112W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-27112W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-27123W Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-27123W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45, PTPRC Submitted name: CD45
MO-AB-46261W Mouse Anti-Horse PTPRC Antibody (MO-AB-46261W) Mouse Horse (Equus caballus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Protein tyrosine phosphatase receptor type C, PTPRC Submitted name: Protein tyrosine phosphatase receptor type C
MO-AB-46262W Mouse Anti-Horse PTPRC Antibody (MO-AB-46262W) Mouse Horse (Equus caballus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Protein tyrosine phosphatase receptor type C, PTPRC Submitted name: Protein tyrosine phosphatase receptor type C
MOFY-0522-FY68 Rat Anti-PTPRC Antibody (MOFY-0522-FY68) Rat Mouse, Human, Feline FC 100µg Alexa Fluor®700, APC, Biotin, CY5, LE/AF, NONE, PE/TXRD, SPRD PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase receptor type C Protein tyrosine phosphatase, receptor type, C
MOFY-0522-FY78 Mouse Anti-PTPRC Antibody (MOFY-0522-FY78) Mouse Human, Horse FC 100Tests Alexa Fluor®700, BIMA, CY5, NONE, PE/CY5.5, PE/CY7, PE/TXRD, SPRD PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase receptor type C Protein tyrosine phosphatase, receptor type, C
CBMOAB-64041FYA Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-64041FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP protein tyrosine phosphatase receptor type C, ptprc Submitted name: Protein tyrosine phosphatase receptor type C
CBMOAB-94615FYA Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-94615FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP CD45 antigen, ptpr Submitted name: CD45 antigen
CBMOAB-94616FYA Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-94616FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP ptprc, protein tyrosine phosphatase receptor type C Protein-tyrosine-phosphatase
CBMOAB-94617FYA Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-94617FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP ptprc, protein tyrosine phosphatase receptor type C Submitted name: Protein tyrosine phosphatase receptor type C
MO-AB-03644Y Mouse Anti-Chicken Ptprc Antibody (MO-AB-03644Y) Mouse Chicken (Gallus gallus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Leukocyte common antigen, CD45, ptprc Submitted name: Leukocyte common antigen, CD45
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