Protein tyrosine phosphatase, receptor type, C
Protein tyrosine phosphatase, receptor type, C, also known as PTPRC, is an enzyme encoded by the PTPRC gene in humans. PTPRC is also called CD45 antigen (CD stands for differentiation cluster) and was originally called Leukocyte Common Antigen (LCA).
The protein product of this gene, most famously CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTP is a signaling molecule that regulates various cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
CD45 is a type I transmembrane protein and exists in various isoforms in all differentiated hematopoietic cells (except red blood cells and plasma cells). CD45 has been shown to be an important regulator of T cell and B cell antigen receptor signal transduction. It plays a role by directly interacting with the components of the antigen receptor complex through its extracellular domain (a form of co-stimulation), or through its cytoplasmic domain to activate various Src family kinases required for antigen receptor signal transduction. CD45 can also inhibit JAK kinase, so it can be used as a negative regulator of cytokine receptor signal transduction.
Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00049FYA) (CAT#: CBMOAB-00049FYA)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00050FYA) (CAT#: CBMOAB-00050FYA)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00051FYA) (CAT#: CBMOAB-00051FYA)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Cattle PTPRC Antibody (CBMOAB-00052FYA) (CAT#: CBMOAB-00052FYA)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Dog PTPRC Antibody (CBMOAB-00136FYA) (CAT#: CBMOAB-00136FYA)
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- Host species: Mouse
- Species Reactivity: Dog (Canis lupus familiaris)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Rabbit PTPRC Antibody (CBMOAB-00180FYA) (CAT#: CBMOAB-00180FYA)
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- Host species: Mouse
- Species Reactivity: Rabbit (Oryctolagus cuniculus)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Alpaca PTPRC Antibody (CBMOAB-00218FYA) (CAT#: CBMOAB-00218FYA)
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- Host species: Mouse
- Species Reactivity: Alpaca (Vicugna pacos), Llama (camel)
- Application: FC
- Size: 100µg
- Conjugate: None
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Rhesus PTPRC Antibody (MO-AB-05415W) (CAT#: MO-AB-05415W)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Protein-tyrosine-phosphatase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Mouse Anti-Cattle PTPRC Antibody (MO-AB-18836R) (CAT#: MO-AB-18836R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: WB, ELISA
- Protein: Protein-tyrosine-phosphatase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: PTPRC protein, Fragment, PTPRC
Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-25498W) (CAT#: MO-AB-25498W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Protein-tyrosine-phosphatase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Protein tyrosine phosphatase, receptor type, C, PTPRC
Mouse Anti-Chimpanzee PTPRC Antibody (MO-AB-26853W) (CAT#: MO-AB-26853W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Submitted name: CD45
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: CD45, PTPRC
Mouse Anti-Horse PTPRC Antibody (MO-AB-46261W) (CAT#: MO-AB-46261W)
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- Host species: Mouse
- Species Reactivity: Horse (Equus caballus)
- Application: WB, ELISA
- Protein: Submitted name: Protein tyrosine phosphatase receptor type C
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Protein tyrosine phosphatase receptor type C, PTPRC
Rat Anti-PTPRC Antibody (MOFY-0522-FY68) (CAT#: MOFY-0522-FY68)
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- Host species: Rat
- Species Reactivity: Mouse, Human, Feline
- Application: FC
- Protein: Protein tyrosine phosphatase, receptor type, C
- Size: 100µg
- Conjugate: Alexa Fluor®700, APC, Biotin, CY5, LE/AF, NONE, PE/TXRD, SPRD
- Alternative Names: PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase receptor type C
Mouse Anti-PTPRC Antibody (MOFY-0522-FY78) (CAT#: MOFY-0522-FY78)
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- Host species: Mouse
- Species Reactivity: Human, Horse
- Application: FC
- Protein: Protein tyrosine phosphatase, receptor type, C
- Size: 100Tests
- Conjugate: Alexa Fluor®700, BIMA, CY5, NONE, PE/CY5.5, PE/CY7, PE/TXRD, SPRD
- Alternative Names: PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase receptor type C
Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-64041FYA) (CAT#: CBMOAB-64041FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Protein tyrosine phosphatase receptor type C
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: protein tyrosine phosphatase receptor type C, ptprc
Mouse Anti-Zebrafish ptprc Antibody (CBMOAB-94617FYA) (CAT#: CBMOAB-94617FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Protein tyrosine phosphatase receptor type C
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: ptprc, protein tyrosine phosphatase receptor type C
Mouse Anti-Chicken Ptprc Antibody (MO-AB-03644Y) (CAT#: MO-AB-03644Y)
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- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus)
- Application: WB, ELISA
- Protein: Submitted name: Leukocyte common antigen, CD45
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Leukocyte common antigen, CD45, ptprc