Mouse Anti-Arabidopsis ATM Antibody (CBMOAB-24677FYC)


Cat: CBMOAB-24677FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO24677FC
SpecificityThis antibody binds to Arabidopsis ATM.
FormatLyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Product OverviewMouse Anti-Arabidopsis ATM (clone MO24677FC) Antibody (CBMOAB-24677FYC) is a mouse antibody against ATM. It can be used for ATM detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesATM Serine/Threonine Kinase; Ataxia Telangiectasia Mutated; A-T Mutated; EC 2.7.11.1; Ataxia Telangiectasia Mutated (Includes Complementation Groups A, C And D); TEL1, Telomere Maintenance 1, Homolog (S. Cerevisiae); TEL1, Telomere Maintenance 1, Homolog; Serine-Protein Kinase ATM; AT Mutated
UniProt IDQ9M3G7
Protein RefseqThe length of the protein is 3856 amino acids long. The sequence is show below: MKLQNPDKKTLREGFSQESSVVALDSGVLAMSGLKCDGKFPVKDVLMEEGGDKVRKIQVSGGNISLVVDFSGARTSSNNFFESNASCVNENLVKGNGYREDETQEFLVGNLVWVMTKYKKWWPGEVVDFKADAKESFMVRSIGQSHLVSWFASSKLKPFKESFEQVLNQRNDNGFFDALQKAMSLLSNSLKLDMTCSCIADGNGIVSAQNITTRKNKPLILREFSVDRLEPKEFVTQLKNIAKCVLNAGVLESTVMQSQLSAFYTLFGHKQIPMAQLHENEGRKSFTAKMSDSKFIGSPSICAGNSRKRFRKEWFRKFVSEVDNVSARDDLVNVPPSDLISKLKLLAVGYNCSEETENIGLFEWFFSKFRISVYHDENAYKMQLANMAGFKDLMLATNANRGTVQKTLKSKKIGKSKMEPLNGVSVADTEQKTFELQISKKSNIESLNGVSVADTEQKTFELQILEKSNIESLNGVSTPNIDHEASKSNNSGKTKINHIIGHSNFPSSVAKVQLAKDFQDKLLVQAPDRKAMTADTLSRPAAILVPDLNSGGNALGTAEFDHMQRPETLIQHNVCPQEEKTPRSTILNFQVTAHQGVSGTQFVSSQPTSYKHFTSADLFTYSGKKKRGRKRKNAEELPIVAHASATTGIPDLNGTNTEPTLVLPQVEPTQRRRRRKKEESPNGLTRGITILFLKFSSQVSMPSRDDLTSTFSAFGPLDSSETHVSEEFSGAQVAFVSSADAIEAVKSLEKANPFGETLVNFRLQQKLITVQRNIAPRMPVISHVSPVPKPNNIPTSMDAMRQNLLMMTAMLEKSGDSLSRETKAKLKSEITGLLEKDGVKLLNTWLEGERSITFCRFLSQNTAKLKLDEIPNAETWPFLVKLLLQCVSMEVSGSKRRMPKPTFAKTLRVVVQRTEETKFPGVQFPLLSMAKTLFTHVHDILSNTPSFQSEYGTILRHLLEIKEYRFQMRKRTYSSLVLLYMERAETGFCEKNSGQHSQKEEAFRYILTLQSLLENSPGDFPDDLREEIVNGLIHIFSSVRDEGKLSRKLIECVNTFLLKDGPNLGSLSLEIHNAVEQFVFRCWLTTHDKNLKEILVSYGRLQLNLTRDSSESSSLVEQLLDVVTRELDLGSSSSSASWGDTTKDEKLGALSSYQNSLVELAAHVFYRACVNTSRPSLSEKRARRQHIAMRMVDALTEGKWLWCAAFGCLVRNYCARINMDLLIYWFEAICTNFQRLLEDASMRRSYDGLLWTLRSLQGLSSGLSLPDITMDISKSSASSSELDRGWQSIWSSLIHGLATFSSMSVIVDAVLVLLGSIISSNHITVKILPQEVWDHQLFRHIPSEPALYFIACYFSRMGCQGNLQDDLHLRRNLLRAVCAPLSWKVRLTLDERMVQLLPAAAFSLCAGFKVSLPLPKEHLPTPSQWDVCEQIDDVDRERNFGLFECSVEALTRICSNSSKISGCQVPDVVQLPLVLRDPLLHDMDIYFLSIIPEVKEKGPLSDIFMGCALLCHFMHGSYITRKGKGSSSFFLKACQYLLEGLDHAVESVSKSLNDLQRRGSLGFGSDFNEKGSIIVSLRSFTQSPVFSNRRDQNLLGASYDFVIHSLENLLRSFAKVYEEYTEHAWNTHSDTVPSKSLAPDSPEVGRIVDMDLDLAEDTKERDIIAAGGKAVPGLPVSMGNWKLGMVSLISCFSPVLQFPTWDVLYNLLEKESDPKVLENILYHLCKLSCLTSIPKVDDLVIFLDGMLSTQVKMKRNCLNIVTALHVLLHTLSSSRRDSSGVEKNCGLSLKEAESFQVFVQLGAMVNKVSEFGLLGWFGRVKLINCICDLVLLNPQTGQTMIERLLLMLSDSDYRVRFVLARQIGILFQTWDGHEALFQDICSSFGIKLVTSSKEKLVTAKDVLAVGPQPRQKMETVIITLMHLAYHSENIELQAVFMMCAVSAKDPCQRELIIAALDNLSAQLHYPSRFKYLEELLGPILFHWIASGVSLAGLIETSQLFIPNAEPKYFIHFCSHWLLPALLLHEDHTNLDWVAKMAGQPVVVLVKENFVPIFSICMGLHCSKTSECDKGAMVLQNSILYVGETSENERDKLIKQNMVSIVSFILSCASSSPEPPVPTFSRDTISLAVQTVVDGFLENTDYPKNAAITDRINIFRPDRVFMFITEMHYRMSAACHHRHTRHHLAALEELTILLGHRALVPSSLNYIFNLVGQFIGYPSLQDQCCSIASCLLDLFKSNPAKEIVSVLGDQLQFLVSKLVTCCIDAEADTKISGAKSSQLVNLLHKLVVSSDSSLNEDIRDLEPLPDLKYFQVIRESHIRICEAYSPRNHLLKVEHSTFLIYIFLEILSLSNFLFLSCSTIQQCSRRSNYLPPRFLSRSLQALHNKLIASEVSQEDTNGETAETFWQSDDEIVNAVWTLVRVSASDEADSMRLLVSDFLSRIGIRDPHTVVFHLPGNLVSMHGLQGFGHNTGSKVRSLTENGISDETLITLLNFLKKYLLDDSVKIIDVTSQTLRGILSTERGQQALSSFDSCERALIEVHGRGVNLDIVEKILLDSQKQFKAEKFSLETPEVWSTDNKNFDRWICQLVYCMIALCEDVPIRLCQNIALLKAEISELLFPSVVVSLAGRIGMDINLHDLITSQVKEHIFTDSNKLTKSKQVMLNTLNELRMCYVLERSIFSGQTKREKNSRSCSTAAKIRDVESGSNGMAASITTNWEKVYWLSIDYLVVAGSAVVCGAYLTASMYVEYWCEEKFGNLSLGDPDFSYHDKLPDHVEILVSAITRINEPDSLYGVIHSNKLSAQIITFEHEGNWTRALEYYDLQARSQKMVVPSSLSENLEVEQFQPTTSARHSVFGEGEVQRQPFKGLIRSLQQTGCMHVLDLYCRGLTSREGCFQYDPEFIELQYEAAWRAGKWDFSLLYPQTHCQPLQHAKNNNYHESLHCCLRALQEGDYDGFYGKLKDTKKELVLSISRASEESTEFIYSTVVKLQILHHLGLVWDLRWTTSSHQSVHGYLVKQMACVDPVIPTMDQLSWLNKDWNSIITQTQLHMTLLEPFIAFRRVLLQILGCEKCTMQHLLQSASLLRKGTRFSHAAASLHEFKFLCARSNGQQPVPDWLGKLEEAKLLHAQGRHEVSISLANYILHNYQLKEEASDIYRVIGKWLAETRSSNSRTILEKYLRPAVSLAEEQSSKICKRLVDRQSQTWFHLAHYADALFKSYEERLSSSEWQAALRLRKHKTKELEVFIKRFKSSKKAEQSDYSLKIQDLQKQLTMDKEEAEKLQVDRDNFLKLALEGYKRCLEIGDKYDVRVVFRQVSMWFSLASQKNVIDNMLSTIKEVQSYKFIPLVYQIASRLGSSKDESGSNSFQSALVSLIRKMAIDHPYHTILQLLALANGDRIKDNQRSRNSFVVDMDKKLAAEHLLQDVSHYHGPMIRQMKQLVDIYIKLAELETRREDTNRKVALPREIRSVKQLELVPVVTATIPVDRSCQYNEGSFPFFRGLSDSVTVMNGINAPKVVECFGSDGQKYKQLAKSGNDDLRQDAVMEQFFGLVNTFLHNNRDTWKRRLAVRTYKVIPFTPSAGVLEWVDGTIPLGDYLIGSSRSEGAHGRYGIGNWKYPKCREHMSSAKDKRKAFVDVCTNFRPVMHYFFLEKFLQPADWFVKRLAYTRSVAASSMVGYIVGLGDRHAMNILIDQATAEVVHIDLGVAFEQGLMLKTPERVPFRLTRDIIDGMGITGVEGVFRRCCEETLSVMRTNKEALLTIVEVFIHDPLYKWALSPLKALQRQKETEDYDGMNLEGLQEEFEGNKDATRALMRVKQKLDGYEGGEMRSIHGQAQQLIQDAIDTDRLSHMFPGWGAWM.
For Research Use Only | Not For Clinical Use.

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