Connect with Us at the Upcoming Events

With in-person events back again, Creative Biolabs is excited to greet you at the upcoming international conferences. Meet our team at 2022 BIO International Convention in June (booth #1754) and at the 13th Annual World ADC San Diego in September (booth number to be updated) for expert consultation on your drug discovery. Shoot an email to arrange an in-person meeting!

Our Modelorg-service

Fab Abzyme Cutting Service

Overview

Fab Abzyme Cutting Service

Creative Biolabs has established a technical platform to obtain antibody Fab fragments with the use of specific proteases, which can greatly satisfy your experimental research needs. We have many years of extensive experience in custom model organism antibdy production, from gene expression or peptide synthesis to antibody labeling and avi-tag biotinylated antibody service.

Enzyme Classification and Advantages

The Fab-Cutter A and Fab-B genes are both derived from Streptococcus pyogenes (S. pyogenes), expressed by E. coli, and obtained through multi-step purification. For different subtypes of human, mouse, sheep, goat, and other species, the enzyme can perform rapid single-point digestion of immunoglobulin IgG.

Classification Advantages
  • Fab-Cutter A
  • The enzyme cleavage site is located above the hinge region of the immunoglobulin IgG
  • Acquire Fab fragments and dimeric Fc fragments
  • Single enzyme cutting site, cutting fast
  • Fab-Cutter B
  • The enzyme cleavage site is located below the hinge region of the immunoglobulin IgG
  • Acquire F(ab')2 fragments and dimeric Fc fragments
  • Can also be applied to mouse IgG2a and IgG3
  • Single enzyme cutting site, cutting fast

Workflow of Our Service

Scientists at Creative Biolabs are dedicated to customizing a comprehensive project plan per your needs, allowing you to spend the least amount of time to achieve your expected results.

Workflow of Our Service

  • We provide a variety of antibodies for you to customize, just contact us for antibody resources
  • According to your application scenarios, we provide you with digestion solutions
  • We provide professional digestion experiment service

Features at Creative Biolabs

Creative Biolabs has extensive experience in Fab abzyme cutting service. Our scientific team is committed to studying in the field for many years, with rich experience. The digestion products we obtained have higher quality and can be used for pilot trials with a small amount of antibody.

  • We have independently developed Fab cutter A and Fab cutter B to prepare fragmented antibodies.
  • Fab / F (ab ') 2 is prepared from the two sites around the hinge region of IgG.
  • The enzyme digestion site is single, the cutting efficiency is high.
  • The experiment period is short and can be delivered in 1-2 weeks.
Creative Biolabs can provide a full range of services included: avi-tag biotinylated antibody service, fluorescently labeled antibody service and Fab abzyme cutting service to fulfill your wide range of demands. At the same time, Creative Biolabs developed and commercializes a series of innovative integrated services. We have the capacity of producing antibodies in large scale for diagnostic industry. If you have any questions, please feel free to contact us.
For Research Use Only | Not For Clinical Use.

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