Glycobiology, also known as glycan, is the study of the structure, biosynthesis, biology, and evolution of saccharides that are widely distributed in nature in all living forms. Glycobiology is a rapidly expanding field of study that is critical for both cellular biology and studies of carbohydrate-based drugs and therapeutics:

  • Glycans play a role in communication between cells and their external environment.
  • Glycosylation is important for protein folding and quality control and defines the adhesive properties of proteins and cells.
  • Glycans play an important role in the development of multicellular organisms and their functions are determined by their unique structures.
  • Glycosylation is an important determinant of the efficacy of biologics such as therapeutic antibodies.

Research Area of Glycobiology in Different Species

  • Yeasts

As biopharmaceuticals with humanized N-linked oligosaccharides, the suppression of yeast-specific O-mannosylation is important to reduce immune response and to improve heterologous protein productivity in the production of biopharmaceuticals. Present study demonstrated that Saccharomyces cerevisiae strain is capable of producing a glycoprotein with humanized Man5GlcNAc2 N-linked oligosaccharides, an intermediate of mammalian hybrid- and complex-type oligosaccharides while suppressing O-mannosylation. This strain was generated by firstly introducing msdS encoding α-1,2-mannosidase into a strain synthesizing Man8GlcNAc2 N-linked oligosaccharides, then disrupting PMT1 and PMT2, using a mutagenesis technique that is based on the disparity theory of evolution and finally disrupting vacuolar proteases PEP4 and PRB1.

  • Rice

Although the differences in protein glycosylation between sexes have already been observed in the rice pest insect Nilaparvata lugens (N. lugens), the functionality of differential N-glycosylation between sexes is yet unknown. Recent study indicated that comparison of N-glycopeptides sites from the adult stages of N. lugens revealed striking differences in protein N-glycosylation between sexes. Additionally, differential glycan composition between males and females was observed for proteins shared across sexes.

  • Arabidopsis thaliana (Arabidopsis)

N-glycosylation plays multiple roles in regulating stress tolerance of plants. Study has shown that an obvious decrease in photosynthetic capacity and dry mass were detected in alg3-3 and cgl1-1, two typical mutants in N-glycosylation process of Arabidopsis. The maximal photochemical efficiency of PSII, which reflected the photochemical of plant, decreased significantly in cgl1-1. Also, a similar tendency was observed in alg3-3. Besides, N-glycosylation was also required to maintain the stability of a chloroplast-located protein CAH1, which was closely related to photosynthesis.

Creative Biolabs offers a comprehensive range of monoclonal, polyclonal, and secondary antibodies. All our antibodies provide high levels of specificity and affinity to target antigens. We also provide a range of cell line controls for reliable antibody validation. For further details, please feel free to contact us.


  1. Lakshminarayanan, Abirami.; et al. Studying glycobiology at the single-molecule level. Nature Reviews Chemistry. 2018.

Our provided featured target antibody products including but not limited to:

Cat# Product Name Host species Species Reactivity Application Size Conjugate Alternative Names Protein
CBMOAB-00431HCB Mouse Anti-C. elegans AGL1 Antibody (CBMOAB-00431HCB) Mouse C. elegans (Caenorhabditis elegans) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP AGL (Amylo-1,6-GLucosidase, 4-alpha-glucanotransferase) glycogen debranching enzyme, agl-1 4-alpha-glucanotransferase
CBMOAB-04249HCB Mouse Anti-C. elegans GALT1 Antibody (CBMOAB-04249HCB) Mouse C. elegans (Caenorhabditis elegans) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Protein GALT-1, galt-1 Beta-1,4-galactosyltransferase galt-1
MORAB-011F Anti-ALG6 Antibody (Cat MORAB-011F), Human IgG Human Saccharomyces cerevisiae IA 0.5mg, 1mg, 10mg None ALG6, YOR002W, UNA544 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
MOFAB-008W Rabbit Anti-PPP1R3G Antibody (MOFAB-008W) Rabbit Zebrafish ELISA, WB, IP Inquiry None PPP1R3G, PPP1R3G PPP1R3G
MOFAB-030W mouse Anti-Rubisco Antibody (MOFAB-030W) mouse Rice IA Inquiry None Ribulose-1, 5-bisphosphate carboxylase/oxygenase, Rubisco Ribulose-1, 5-bisphosphate carboxylase/oxygenase
MOFAB-184W Rabbit Anti-UGPase Antibody (MOFAB-184W) Rabbit Arabidopsis, Canola, Brassica Oleracea WB, IF Inquiry None Probable UTP--glucose-1-phosphate uridylyltransferase 2, EC, UDP-glucose pyrophosphorylase 2, UDPGP 2, UGPase 2, At3g03250, UGPase, UGPase Probable UTP--glucose-1-phosphate uridylyltransferase 2
MOF032922W82 Rabbit Anti-Gliadin Antibody (MOF032922W82) Rabbit Wheat gliadin ELISA, IHC-P, IHC-Fr, ICC, IF 100µL, 200µL, 50µL NONE Celiac disease, gliadin - wheat ergot protein
MOFY-0522-FY12 Mouse Anti-CD1.1 Antibody (MOFY-0522-FY12) Mouse Chicken FC, IHC, IP 0.5mg Biotin, FITC, NONE CD1.1 CD1.1 antigen
MOFY-0522-FY20 Mouse Anti-B6.1 Antibody (MOFY-0522-FY20) Mouse Chicken FC, IHC, IP 0.5mg Biotin, FITC, NONE, PE B6.2, Bu-1, Bu-1b LOC396098
MOFY-0522-FY22 Mouse Anti-B6.1 Antibody (MOFY-0522-FY22) Mouse Chicken FC 100µg Alexa Fluor®488, Alexa Fluor®647, Biotin, FITC, NONE, PACBLU, PE B6.2, Bu-1, Bu-1b LOC396098
MOFY-0522-FY23 Mouse Anti-CD44 Antibody (MOFY-0522-FY23) Mouse Chicken, Turkey, Pigeon FC, IHC 0.5mg APC, Biotin, FITC, NONE, PE, SPRD CD44 Molecule (Indian Blood Group), Hematopoietic Cell E- And L-Selectin Ligand, GP90 Lymphocyte Homing/Adhesion Receptor, Chondroitin Sulfate Proteoglycan 8, Extracellular Matrix Receptor III, Heparan Sulfate Proteoglycan, Phagocytic Glycoprotein 1, Hyaluronate Receptor, Hermes Antigen, CD44 Antigen, ECMR-III, HUTCH-I, Epican, CDW44, MDU2, MDU3 CD44 Molecule (Indian Blood Group)
MOFY-0522-FY29 Mouse Anti-B6.1 Antibody (MOFY-0522-FY29) Mouse Chicken FC, IHC, IP, Apop 0.5mg Biotin, FITC, NONE, PE Bu-1a, B6.2, Bu-1, Bu-1b LOC396098
MOFY-0522-FY122 Rat Anti-Laminin Antibody (MOFY-0522-FY122) Rat Human, Mouse, Swine IHC, IF, IHC-Fr 100µg NONE Laminin Laminin
MOFY-0522-FY203 Mouse Anti-BLV gp51-G Antibody (MOFY-0522-FY203) Mouse Bovine RIPA, FC, ELISA 100µg NONE BLV gp51-G, Bovine Leukemia Virus (BLV) MAb gp51-G Bovine Leukemia Virus (BLV) MAb gp51-G
MOFY-0522-FY204 Mouse Anti-BLV gp51-G D-D Antibody (MOFY-0522-FY204) Mouse Bovine RIPA, FC, WB 100µg NONE BLV gp51-G D-D', Bovine Leukemia Virus (BLV) MAb gp51 D-D' Bovine Leukemia Virus (BLV) MAb gp51 D-D'
MOFY-0522-FY50 Rat Anti-ICAM1 Antibody (MOFY-0522-FY50) Rat Mouse, Porcine FC, IHC, WB, IP 0.5mg Alexa Fluor®700, APC, Biotin, FITC, LE/AF, NONE, PACBLU, PE Intercellular Adhesion Molecule 1 Intercellular Adhesion Molecule 1
MOFY-0522-FY60 Mouse Anti-SIRPA Antibody (MOFY-0522-FY60) Mouse Porcine FC 100µg Alexa Fluor®488, Biotin, FITC, NONE, PE Signal Regulatory Protein Alpha, CD172 Antigen-Like Family Member A, Inhibitory Receptor SHPS-1, Macrophage Fusion Receptor, PTPNS1, SHPS1, SIRP, P84, BIT, MFR, Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs, Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs, Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1, Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1, Tyrosine Phosphatase SHP Substrate 1, Signal-Regulatory Protein Alpha-1 Signal Regulatory Protein Alpha
MOFY-0522-FY70 Mouse Anti-CD8 Antibody (MOFY-0522-FY70) Mouse Feline, Lion, Tsushima FC, IHC, IP 0.5mg Biotin, FITC, NONE, PE CD8 alpha chain, CD8 CD8 alpha chain
MOFY-0522-FY82 Mouse Anti-FBN1 Antibody (MOFY-0522-FY82) Mouse Human, Bovine, Japanese IHC, EM, WB, IP 200µg Biotin, FITC, NONE Fibrillin 1, Asprosin, FBN, Fibrillin 1 (Marfan Syndrome), Fibrillin-1 Preproprotein, Marfan Syndrome, Fibrillin 15, Fibrillin-1, GPHYSD2, ACMICD Fibrillin 1
MOFY-0722-FY262 Rabbit Anti-FSHb Antibody (MOFY-0722-FY262) Rabbit Pig, Mouse WB, IHC, ICC, IP 100µL None Follicle Stimulating Hormone Beta Subunit, Follicle Stimulating Hormone, Beta Polypeptide, Follitropin, Beta Chain, FSH-Beta, FSH-B, Follicle-Stimulating Hormone Beta Subunit, Follitropin Subunit Beta, Follitropin Beta Chain, HH24 Follicle Stimulating Hormone Beta Subunit
MOFY-0722-FY268 Rabbit Anti-FGB Antibody (MOFY-0722-FY268) Rabbit Pig WB, IHC, ICC, IP 100µL None Fibrinogen Beta Chain, Fibrinogen, B Beta Polypeptide, Epididymis Secretory Sperm Binding Protein Li 78p, Beta-Fibrinogen, HEL-S-78p Fibrinogen Beta Chain
MOFY-0722-FY317 Rabbit Anti-TG Antibody (MOFY-0722-FY317) Rabbit Bovine WB, IHC, ICC, IP 100µL None Thyroglobulin, AITD3, TGN, Tg TG Gene(Protein Coding) Thyroglobulin
MOFY-0722-FY423 Rabbit Anti-FN1 Antibody (MOFY-0722-FY423) Rabbit Goat WB, IHC, ICC, IP 100µL None Fibronectin 1, Cold-Insoluble Globulin, Migration-Stimulating Factor, CIG, FN, Fibronectin, GFND2, SMDCF Fibronectin 1
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