Mouse Anti-FBN1 Antibody (MOFY-0522-FY82)


Cat: MOFY-0522-FY82
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Specifications

Host speciesMouse
Species ReactivityHuman, Bovine, Japanese
ImmunogenMicrofibrils from the zonule-like organ of the bull's eye
FormatLiquid or Lyophilized
BufferBBS, pH 8.2
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIHC, EM, WB, IP
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]
Alternative NamesFibrillin 1; Asprosin; FBN; Fibrillin 1 (Marfan Syndrome); Fibrillin-1 Preproprotein; Marfan Syndrome; Fibrillin 15; Fibrillin-1; GPHYSD2; ACMICD;
Gene ID281154(Bovine)
UniProt IDP98133(Bovine)
For Research Use Only | Not For Clinical Use.
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