Rabbit Anti-FGB Antibody (MOFY-0722-FY268)


Cat: MOFY-0722-FY268
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Specifications

Host speciesRabbit
Species ReactivityPig
ImmunogenNative Fibrinogen (FG)
FormatLiquid or Lyophilized
Buffer0.01M PBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-3 µg/mL
IHC: 5-30 µg/mL
ICC: 5-30 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Alternative NamesFibrinogen Beta Chain; Fibrinogen, B Beta Polypeptide; Epididymis Secretory Sperm Binding Protein Li 78p; Beta-Fibrinogen; HEL-S-78p;
For Research Use Only | Not For Clinical Use.
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