Mouse Anti-SIRPA Antibody (MOFY-0522-FY60)

Cat: MOFY-0522-FY60

Certificate of Analysis Lookup
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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
MOFY-0522-FY60	Monoclonal	Porcine, Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Horse (Equus caballus), Marmoset	FC			100 µg	Inquiry
CBMOAB-00025FYA	Monoclonal	Cattle (Bos taurus)	FC	F00025FYA		100 µg	Inquiry
MO-AB-16442W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO16442W		100 µg	Inquiry
Protein Refseq: The length of the protein is 508 amino acids long. The sequence is show below: MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLHCTATSLIPVGPIQWFRGAGPSRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNQLSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK.
MO-AB-46524W	Monoclonal	Horse (Equus caballus)	WB, ELISA	MO46524W		100 µg	Inquiry
Protein Refseq: The length of the protein is167 amino acids long. The sequence is show below: SHGFSPRNITLKWFKNGNELSASQTNVDPEENNVSYNISSTAQVVLAPGDVRSQVICEVAHITLQGAPPLRGTANLSETIRVPPTLEVSQHPTAENQENITCQANKFYPQQLKLTWLENGNVTRTETASTLIENKDGTFSWTSWLLVNSSARREDVVLTCQVEHDGQ.
MO-AB-64402W	Monoclonal	Marmoset	WB, ELISA	MO64402W		100 µg	Inquiry
Protein Refseq: The length of the protein is 510 amino acids long. The sequence is show below: MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVGQPEKSVSVAAGETATLHCTVTSLVPVGPIQWFRGAGPGRELIYNQKEGQFPRVTAVADQTKRNNMDHSIRISNITPADAGTYYCVKFRKASPIDVELKSGPGTELSVRAKPSAPVVSGPATRVTPEDTVSFTCESHGFSPRDITLKWFKNANELSALQTTVDPAGESVSYSIRSTARVGLTRGDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTHQPMRAENQVNVTCQVKKFYPQSLQLTWLENGNVSRTETASTLIENKDGTYNWASWLLVNSSAHRDGVVLTCQVEHDGQPAVSKSLRLEVSAHRKEQGSDTAAEKTGTNERNIYIVVGVVCTLLVALLLAALYLVRVRQKKAQGSTSSTRLHEPEKNAREITQVQSLIQDTNDITYADLNLPKGKKPAPRAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK.
MO-AB-20142R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO20142R		100 µg	Inquiry
Protein Refseq: The length of the protein is 506 amino acids long. The sequence is show below: MEPARPAPGRLRPLLCLLLAASNAWTGTAGDGELQVIQPERSVSVAAGETATLHCTVTSLSPVGPIKWFKGTGPGREFIYSQKEAPFPRVTNVSDATKRNNMDFSIRISNITPADAGVYYCVKFRKEERGDMEFKSGPGTHLTVSAKPSPPVLSGPTVRATPEQTVNFTCTSHGFSPRNISLKWFKNGNELSASQTSVDPEDNNVSYSINSTTKVLLATGDVHSQVICEVAHVTLQGGPPLRGTANLSETIRVPP.

Specifications

Host species	Mouse
Species Reactivity	Porcine, Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Horse (Equus caballus), Marmoset
Immunogen	Fresh dd miniature porcine thymocytes
Format	Liquid or Lyophilized
Buffer	PBS
Regulatory Status	For Research Use Only. Not For Clinical Use.
Shipping	Gel Pack
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use

Application Information

Application	FC
Application Notes	The optimal dilution should be determined by the end user.

Target

Introduction

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]

Alternative Names

Signal Regulatory Protein Alpha; CD172 Antigen-Like Family Member A; Inhibitory Receptor SHPS-1; Macrophage Fusion Receptor; PTPNS1; SHPS1; SIRP; P84; BIT; MFR; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; Tyrosine Phosphatase SHP Substrate 1; Signal-Regulatory Protein Alpha-1;

For Research Use Only | Not For Clinical Use.

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