Mouse Anti-SIRPA Antibody (MOFY-0522-FY60)
Cat: MOFY-0522-FY60
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Porcine |
| Immunogen | Fresh dd miniature porcine thymocytes |
| Format | Liquid or Lyophilized |
| Buffer | PBS |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | FC |
| Application Notes | The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | Signal Regulatory Protein Alpha; CD172 Antigen-Like Family Member A; Inhibitory Receptor SHPS-1; Macrophage Fusion Receptor; PTPNS1; SHPS1; SIRP; P84; BIT; MFR; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; Tyrosine Phosphatase SHP Substrate 1; Signal-Regulatory Protein Alpha-1; |
See other products for " SIRPA "
| MO-AB-46524W | Mouse Anti-Horse SIRPA Antibody (MO-AB-46524W) |
| MO-AB-16442W | Mouse Anti-Chimpanzee SIRPA Antibody (MO-AB-16442W) |
| CBMOAB-00025FYA | Mouse Anti-Cattle SIRPA Antibody (CBMOAB-00025FYA) |
| MO-AB-64402W | Mouse Anti-Marmoset SIRPA Antibody (MO-AB-64402W) |
| MO-AB-20142R | Mouse Anti-Cattle SIRPA Antibody (MO-AB-20142R) |
For Research Use Only | Not For Clinical Use.
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