Mouse Anti-Arabidopsis MED12 Antibody (CBMOAB-36335FYC)
Cat: CBMOAB-36335FYC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Clone | MO36335FC |
| Specificity | This antibody binds to Arabidopsis MED12. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. |
| Product Overview | Mouse Anti-Arabidopsis MED12 Antibody is a mouse antibody against MED12. It can be used for MED12 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Mediator Complex Subunit 12; Thyroid Hormone Receptor-Associated Protein Complex 230 KDa Component; Trinucleotide Repeat-Containing Gene 11 Protein; Activator-Recruited Cofactor 240 KDa Component; OPA-Containing Protein; CAG Repeat Protein 45; TRAP230; TNRC11; ARC240; CAGH45; HOPA; Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog (S. Cerevisiae); Trinucleotide Repeat Containing 11 (THR-Associated Protein, 230 KDa Subunit); Trinucleotide Repeat Containing 11 (THR-Associated Protein, 230kDa Subunit) |
| UniProt ID | H3K2Y6 |
| Protein Refseq | The length of the protein is 2235 amino acids long. The sequence is show below: MQRYHAANCTSAVNNSAIGGASARDSGRADSSSIGNYSLNSRRPPPLTPYKLKCEKDGLNSRLGPPDFHPPTSNSPEENLTKEYVQFGYKETVDGLKESEEIILSQVHTFSKPVVHKCKEAVRKCLRAINESRALKRKAGQVYGVPLSGSLLCKPGFPEQRSCGEETKKRWIESLSQQHKRLRSLADNIPGYRRKTLFEVLIRNNVPLLRATWFIKVTYLNQVRPSPAAISSGTPDKTQASRCEQWTKDVIEYLQYLLDELLSRNSSFPAQQTRDRSPQMLYTGSMQKNSPASTSLYGEETSLHFKWWYMVRLLQWHHAEGLLFPNLIVDWVLKLLQEKEIFEILQLLLPIVYGVLESIVLSQTYVQSLVAIAVRFIQEPAPGGSDLVDNSRRAYTLSALIEMVRYLVLAAPDTFVASDFFPLPPSVAACGPNDVSYTSKAYENLEKLRSNSAEISAQFQGRGVLSRFEFLSFDYTISTIQRSADDLAKIASAGYPQHNVAKAVQALDKALSDGDIRAAYSYLFEDLCNGAVDEAWITDVSPCLRSSLRWIGAISTSFVCSVFFLIEWATCDFRDFRAGVPKDIKFSGRKDCSQVYLVIQLLKQKILGGEFTARKGKNCRNNFLGVSKPSGSMDAFESPGPLHDIIVCWIDQHEVHKGGAKRLQLLVFELIRSGIFNPIAYVRQLIVSGMIDVIQPAVDPERRMRHHRILKQLPGCFVHETLEEAQLFGGDKLSEAVRTYSNERRLLLRELLVEKGKYWNNLVLSDQKSKKISTSLSSVIFPRACNAKSNSKGPRKHTKSSVDIRELKERISALLQFPGMSCGVETPVRDEFQNSVKRSSGSVYSKMDQPEATPGCEDCRRAKRPKMNDEKSSCYQGNSPIASDEEDNWWIKKGSKTVESSLKVDPQIEITKQVPRGRQKMARKTQSLAQLQAARIEGSQGASTSHVCDNKVSCPHHGPGVEGENQKVVDVFRTSTPVDMVSVGNSLKQLQFVDKRSIAVWLTTAVRQLVEEPQKSSVRVGQFNRGAPVEEKNTIRWKLGADELYSILFLLDISLDLVSAVKFLLWLLPKANSTPSFAVQGGRNLVTVPRNVENNMCEIGEAILVSSLRRYENILLSADLVPEAMTALMNRAASLMSSNGKISGSAALVYTRYILKRYGSLPSVVEWHNNFKATSEKKLLSELDHTRSGNGEYGNPLGVPAGVDNPDDYLRKKISIGGARPSRVGLSMRDVLQRHVEEATHYLKKLIGTGTMKASLAEKNDDGYQVAQQIVVGLMDCIRQTGGAAQEGDPSLVSSAVSAIINSVGLSVARITDFSLGNIYQNHPSGVDSSNIARYILRIHITCLCLLKEALGERQSRVFEIALATESSTALTGVFAPVKGSRGQHQLSPESYDSNANNSTIDMSNGTGKMALSRATKITAAVSALVIGSITHGVITLERIVGLLRLKDYLDFVQFVRRTKSSSNGSARSMGASKVESPIEVYVHWFRLLVGNCKTVSEGLVLELVGESSVVAISRMQRMLPLKLVFPPAYSIIAFVLWRPFVSNSNSNSSVHEDTHRLYQSLTMAFHDVIKHLPFRDVCFRDTQGLYELIVADSTDAEFASVFESHGLDMHLKSVAFAPLRARLFLNSLIDCKVPSSGYSHEGVSEAKNRHQGNGTKLVDKLVSVLDCLQPAKFHWQWVELRLLLNEQALAEKLENHDMPLTDAIRSSCPTSEKPDASENEKNFIQILLTRLLVRPDAVPLFSEVVHLFGRSVEDSMLKQAEWFLAGQDVLFGRKTIRQKLIIVGESKGLPTKPQFWKPWGWCNSSSSDHITANKAGKKRKFEITSIEEGEVIEEGSGSRKVLLPRVLDENSPSVGYGITTERAFVQLVLPCIDQSSDESRSTFVNELVRQFSNIEQQLSSVTNRSTTSNKQMGTASSGSEISSNKGSTRKGLRGGSPSLARRSSANTTDTSPPPSPAALRASMSLRLQFLLRLLPVICGEPSFKNTRHALASTIVRLLGSRVVYEDYAVCSPRSELSKAETESTIDPSSMADLSSEVLFDRLLFVLHGLLSNHQPKWLKPRPSSNESSKDFTLFDRDAAESLQNELSRMQLPDTIRWRIQAAMPILLPSLRCSLSCQPHSVPPTALTLVQPSGSTAAAGTNQRNSPAISKSGTAAAQGKLKPTMLAPHQQQEADNTDVVDPWTLLEDGTSSGLSSSNASNSSDMANLRATCWLKGAVRVRRTDLTYVGSVDDDS. |
See other products for " MED12 "
| MO-AB-58915W | Mouse Anti-Marmoset MED12 Antibody (MO-AB-58915W) |
| CBMOAB-51080FYA | Mouse Anti-Rhesus MED12 Antibody (CBMOAB-51080FYA) |
| MO-AB-27241R | Mouse Anti-Pig MED12 Antibody (MO-AB-27241R) |
| MO-AB-27008W | Mouse Anti-Chimpanzee MED12 Antibody (MO-AB-27008W) |
| CBMOAB-86415FYA | Mouse Anti-Zebrafish med12 Antibody (CBMOAB-86415FYA) |
For Research Use Only | Not For Clinical Use.
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