Mouse Anti-Arabidopsis NUDT15 Antibody (CBMOAB-37699FYC)


Cat: CBMOAB-37699FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO37699FC
SpecificityThis antibody binds to Arabidopsis NUDT15.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Product OverviewMouse Anti-Arabidopsis NUDT15 Antibody is a mouse antibody against NUDT15. It can be used for NUDT15 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesNudix Hydrolase 15; Nucleoside Diphosphate-Linked To Another Moiety X Hydrolase 15; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15; MutT Homolog 2; MTH2; Probable 7,8-Dihydro-8-Oxoguanine Triphosphatase NUDT15; Nucleoside Diphosphate-Linked Moiety X Motif 15
UniProt IDQ8GYB1
Protein RefseqThe length of the protein is 285 amino acids long. The sequence is show below: MFLLYRRLPSFARTTTTTLLCKSMEPAITATSSSSFGGGSSRLAALAQQLRQYKPPPSSSFDDSEEMQTDQETAGKVVSQVGFQESIAPLSKDPDRFKPKRAAVLICLFEGDDGDLRVILTKRSSKLSTHSGEVSLPGGKAEEDDKDDGMTATREAEEEIGLDPSLVDVVTSLEPFLSKHLLRVIPVIGILRDKNKFNPIPNPGEVEAVFDAPLEMFLKDENRRSEEREWMGEKYLIHYFDYRTGDKDYMIWGLTAGILIRAASVTYERPPAFIEQCPKFKYPKM.
For Research Use Only | Not For Clinical Use.
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