Mouse Anti-MCM6 Antibody (CBMOAB-06464HCB)


Cat: CBMOAB-06464HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-06464HCB Monoclonal C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Maize (Zea mays), Marmoset, Pig (Sus scrofa), Yeast, Zebrafish (Danio rerio) WB, ELISA MO06464HB 100 µg
CBMOAB-36309FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO36309FC 100 µg
CBMOAB-23519FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO23519FYA 100 µg
CBMOAB-86314FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO86314FYA 100 µg
CBMOAB-02183CR Monoclonal Yeast WB, ELISA MO02183CR 100 µg
MO-AB-14961W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO14961W 100 µg
MO-AB-48693W Monoclonal Maize (Zea mays) WB, ELISA MO48693W 100 µg
MO-AB-58864W Monoclonal Marmoset WB, ELISA MO58864W 100 µg
MO-AB-15463R Monoclonal Cattle (Bos taurus) WB, ELISA MO15463R 100 µg
MO-AB-27222R Monoclonal Pig (Sus scrofa) WB, ELISA MO27222R 100 µg
MO-AB-05080H Monoclonal Frog (Xenopus laevis) WB, ELISA MO05080C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Maize (Zea mays), Marmoset, Pig (Sus scrofa), Yeast, Zebrafish (Danio rerio)
CloneMO06464HB
SpecificityThis antibody binds to C. elegans MCM6.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.
Product OverviewMouse Anti-C. elegans MCM6 Antibody is a mouse antibody against MCM6. It can be used for MCM6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDNA replication licensing factor mcm-6; EC 3.6.4.12; mcm-6
UniProt IDP34647
Protein RefseqThe length of the protein is 810 amino acids long. The sequence is show below: MDNIIGGQAQQVEDTDGTRVQNEFSKFLKSFKDQKNEFIYKSAMKELVQPEKNTIFINMQHLYKFSNNLATTIELQYYRVYPFMCEALHLATLDACDESERQQMFKKQLYVSLFNLDAKTKVRELSADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAVEETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRAISEHTERDSVYKIDDIKKYIAFARCFKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEHVEKAAELLNKSIVRVEQPDIALDDDDFDNNIMVVEADKENQRGDDSMDHDGEKENAPKIDIAKLKISFKEYKQLSDVLVLHMRSDEDNQGEDEYDGVKQSALVEWYLSTIEADLETEEDFNVQKTICERVIHRLIHQDHVLLEVEQGEDPTLCVHPNYVIADE.
For Research Use Only | Not For Clinical Use.
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