Mouse Anti-C. elegans PCP1 Antibody (CBMOAB-00125HCB)


Cat: CBMOAB-00125HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO00125HB
SpecificityThis antibody binds to C. elegans PCP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionMitochondrial rhomboid serine protease processing the mitochondrial membrane fusion regulator MGM1, and the cytochrome c peroxidase (CCP1). Required for TIM11 stability, ATP synthase complex assembly, mitochondrial morphology, cytochrome c (CYC1) storage and mitochondrial genome maintenance.
Product OverviewMouse Anti-C. elegans PCP1 (clone MO00125HB) Antibody (CBMOAB-00125HCB) is a mouse antibody against PCP1. It can be used for PCP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPutative serine protease pcp-1; pcp-1
Gene ID176086
UniProt IDP34610
Protein RefseqThe length of the protein is 565 amino acids long. The sequence is show below: MRWFLVLLLVALVSVEASRRSRLFKKLYQKASNYDAAPSNVQTVWYKNMKLDHFTWGDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDKDLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLYGYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNARFQIIQILKCWVDPNCNTIPTISPLPSISIPNGDCKDVVGGYPWGQTTGATVSNSFILAILASLYAMF.

IF

Figure 1 Multipolar nuclear division occurs in polyploid zygotic meiosis. Representative microscopic images of MI in diploid and tetraploid zygotes expressing Pcp1-GFP (SPB) and mCherry-Atb2 (microtubules).

IF

Figure 2 Dynamics of Pcp1 association with the SPB is lost in polyploid zygotes. Representative time-lapse images of meiotic prophase in diploid zygotes expressing Ppc89-GFP and Hrs1-mCherry or Pcp1-GFP and Hrs1-mCherry.

For Research Use Only | Not For Clinical Use.
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