Mouse Anti-Fen1 Antibody (CBMOAB-16738FYA)


Cat: CBMOAB-16738FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-16738FYA Monoclonal Fruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana), Arabidopsis (Arabidopsis lyrata), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Cottonwood (Populus deltoids), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), French-bean, Gorilla, Grape (Vitis vinifera), Hamsters (Cricetinae), Horse (Equus caballus), Human, Mouse, Rat, Monkey, Hamster, Maize (Zea mays), Marmoset, Medaka (Oryzias latipes), Nile tilapia (Oreochromis niloticus), O. anatinus (Ornithorhynchus anatinus), O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Silkworm (Bombyx mori), Zebrafish (Danio rerio) WB, ELISA MO16738FYA 100 µg
CBMOAB-33226FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO33226FC 100 µg
CBMOAB-76318FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO76318FYA 100 µg
MO-AB-00465H Monoclonal Arabidopsis (Arabidopsis lyrata) WB, ELISA MO00465C 100 µg
MO-AB-00479R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00479R 100 µg
MO-AB-06475Y Monoclonal O. anatinus (Ornithorhynchus anatinus) WB, ELISA MO06475Y 100 µg
MO-AB-08061Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08061Y 100 µg
MO-AB-08473W Monoclonal Cat (Felis catus) WB, ELISA MO08473W 100 µg
MO-AB-11359Y Monoclonal O. mykiss (Oncorhynchus mykiss) WB, ELISA MO11359Y 100 µg
MO-AB-12487R Monoclonal Cattle (Bos taurus) WB, ELISA MO12487R 100 µg
MO-AB-15236Y Monoclonal Sheep (Ovis aries) WB, ELISA MO15236Y 100 µg
MO-AB-17784W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO17784W 100 µg
MO-AB-25809R Monoclonal Pig (Sus scrofa) WB, ELISA MO25809R 100 µg
MO-AB-27568W Monoclonal Cottonwood (Populus deltoids) WB, ELISA MO27568W 100 µg
MO-AB-30757W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO30757W 100 µg
MO-AB-33085H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO33085C 100 µg
MO-AB-34742W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34742W 100 µg
MO-AB-36195W Monoclonal French-bean WB, ELISA MO36195W 100 µg
MO-AB-38551W Monoclonal Gorilla WB, ELISA MO38551W 100 µg
MO-AB-39021W Monoclonal Grape (Vitis vinifera) WB, ELISA MO39021W 100 µg
MO-AB-43140W Monoclonal Hamsters (Cricetinae) WB, ELISA MO43140W 100 µg
MO-AB-44725W Monoclonal Horse (Equus caballus) WB, ELISA MO44725W 100 µg
MO-AB-48132W Monoclonal Maize (Zea mays) WB, ELISA MO48132W 100 µg
MO-AB-55387W Monoclonal Marmoset WB, ELISA MO55387W 100 µg
MO-AB-69802W Monoclonal Silkworm (Bombyx mori) WB, ELISA MO69802W 100 µg
MOF032922W147 Monoclonal Human, Mouse, Rat, Monkey, Hamster WB, ICC/IF 100 µg
MO-DKB-00053W Polyclonal A. thaliana (Arabidopsis thaliana) ELISA 100 µg
MO-DKB-00054W Polyclonal A. thaliana (Arabidopsis thaliana) IA 100 µg
MO-DKB-00056W Polyclonal A. thaliana (Arabidopsis thaliana) ELISA, WB 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana), Arabidopsis (Arabidopsis lyrata), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Cottonwood (Populus deltoids), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), French-bean, Gorilla, Grape (Vitis vinifera), Hamsters (Cricetinae), Horse (Equus caballus), Human, Mouse, Rat, Monkey, Hamster, Maize (Zea mays), Marmoset, Medaka (Oryzias latipes), Nile tilapia (Oreochromis niloticus), O. anatinus (Ornithorhynchus anatinus), O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Silkworm (Bombyx mori), Zebrafish (Danio rerio)
CloneMO16738FYA
SpecificityThis antibody binds to fruit fly Fen1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Mitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
Product OverviewMouse Anti-D. melanogaster Fen1 Antibody is a mouse antibody against Fen1. It can be used for Fen1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFlap endonuclease 1; FEN-1; EC 3.1.-.-; Flap structure-specific endonuclease 1; Fen1
UniProt IDQ7K7A9
Protein RefseqThe length of the protein is 385 amino acids long.
The sequence is show below: MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGDDAGIEKFNRRLVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYLTYSEARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCESIKGIGPKRAIELINTYRDIETILDNLDSSKYTVPENWNYKVARELFIEPEVADADSIDLKWVEPDEEGLVKFLCGDRQFNEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPSTPNATNAAKRKAEEAKKSANNKKAKTSGGGRGRRPK.
For Research Use Only | Not For Clinical Use.
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