Mouse Anti-D. melanogaster Met Antibody (CBMOAB-23765FYA)


Cat: CBMOAB-23765FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO23765FYA
SpecificityThis antibody binds to fruit fly Met.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.
Product OverviewMouse Anti-D. melanogaster Met Antibody is a mouse antibody against Met. It can be used for Met detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFI10506p; Methoprene-tolerant, isoform A; Methoprene-tolerant, isoform B; Met; Met-RA
UniProt IDQ9VYW2
Protein RefseqThe length of the protein is 716 amino acids long.
The sequence is show below: MAAPETGNTGSTGSAGSTGSGSGSGSGSGSSSDPANGREARNLAEKQRRDKLNASIQELATMVPHAAESSRRLDKTAVLRFATHGLRLQYVFGKSASRRRKKTGLKGTGMSASPVGDLPNPSLHLTDTLMQLLDCCFLTLTCSGQIVLVSTSVEQLLGHCQSDLYGQNLLQITHPDDQDLLRQQLIPRDIETLFYQHQHHQQQGHNPQQHSTSTSASTSGSDLEEEEMETEEHRLGRQQGEADDDEDHPYNRRTPSPRRMAHLATIDDRLRMDRRCFTVRLARASTRAEATRHYERVKIDGCFRRSDSSLTGGAAANYPIVSQLIRRSRNNNMLAAAAAVAAEAATVPPQHDAIAQAALHGISGNDIVLVAMARVLREERPPEETEGTVGLTIYRQPEPYQLEYHTRHLIDGSIIDCDQRIGLVAGYMKDEVRNLSPFCFMHLDDVRWVIVALRQMYDCNSDYGESCYRLLSRNGRFIYLHTKGFLEVDRGSNKVHSFLCVNTLLDEEAGRQKVQEMKEKFSTIIKAEMPTQSSSPDLPASQAPQQLERIVLYLIENLQKSVDSAETVGGQGMESLMDDGYSSPANTLTLEELAPSPTPALALVPPAPSSVKSSISKSVSVVNVTAARKFQQEHQKQRERDREQLKERTNSTQGVIRQLSSCLSEAETASCILSPASSLSASEAPDTPDPHSNTSPPPSLHTRPSVLHRTLTSTLR.
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MO-AB-31758WMouse Anti-Dog MET Antibody (MO-AB-31758W)
MO-AB-05123HMouse Anti-Frog met Antibody (MO-AB-05123H)
MO-AB-31882HMouse Anti-Soybean MET Antibody (MO-AB-31882H)
MO-AB-19496WMouse Anti-Chimpanzee MET Antibody (MO-AB-19496W)
MO-AB-58990WMouse Anti-Marmoset MET Antibody (MO-AB-58990W)
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For Research Use Only | Not For Clinical Use.
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