Cat: CBMOAB-00294FYA
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | F00294FYA |
| Specificity | This antibody is binds to Mouse NR3C1 and has cross reactivity with Human, Rat, Zebrafish. |
| Format | Liquid |
| Buffer | TBS, pH 7.4 |
| Purification | Purified with Protein A affinity chromatography |
| Cellular Localization | Cytoplasm; Nucleus; Mitochondrion |
Application Information
| Application | WB, FC |
| Application Notes | WB: 1:1,000-1:5,000 FC: 1:50-1:100 |
Target
| Introduction | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). |
| Product Overview | Rabbit Anti-Mouse NR3C1 (clone F00294FYA) Antibody (CBMOAB-00294FYA) is a Rabbit antibody against the NR3C1. It can be used for NR3C1 detection in Western Blot, Flow Cytometry. |
| Alternative Names | Nuclear Receptor Subfamily 3 Group C Member 1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor); Glucocorticoid Receptor; GRL; GR; Nuclear Receptor Subfamily 3, Group C, Member 1 |
| Gene ID | 2908 |
| UniProt ID | P04150 |
See other products for " NR3C1 "
| MO-AB-08996Y | Mouse Anti-Rabbit NR3C1 Antibody (MO-AB-08996Y) |
| MO-AB-15329W | Mouse Anti-Chimpanzee NR3C1 Antibody (MO-AB-15329W) |
| MO-AB-05763H | Mouse Anti-Frog nr3c1 Antibody (MO-AB-05763H) |
| MO-AB-16366Y | Mouse Anti-Sheep NR3C1 Antibody (MO-AB-16366Y) |
| MO-AB-16928R | Mouse Anti-Cattle NR3C1 Antibody (MO-AB-16928R) |
| CBMOAB-89902FYA | Mouse Anti-Zebrafish nr3c1 Antibody (CBMOAB-89902FYA) |
| MOFAB-122W | Sheep Anti-NR3C1 Antibody (MOFAB-122W) |
| MO-AB-27839R | Mouse Anti-Pig NR3C1 Antibody (MO-AB-27839R) |
| MO-DKB-03618W | Rabbit Anti-NR3C1 (AA 1-150, clone ms2109-026) Antibody (Cat MO-DKB-03618W) |
| MO-AB-42171W | Mouse Anti-Guinea pig Nr3c1 Antibody (MO-AB-42171W) |
For Research Use Only | Not For Clinical Use.