Mouse Anti-Rabbit WNT10A Antibody (MO-AB-10490Y)


Cat: MO-AB-10490Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus)
CloneMO10490Y
SpecificityThis antibody binds to Rabbit WNT10A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationExtracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt''s lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
Product OverviewThis product is a mouse antibody against WNT10A. It can be used for WNT10A detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein Wnt; WNT10A
UniProt IDG1TAR3
Protein RefseqThe length of the protein is 417 amino acids long. The sequence is show below: MGSAHPRPWLRLRPRPQPRPPLWALLFFLLLLAAAVPRSAPNDILGLRLPPEPVLNANTVCLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKIPYESPIFSRGFRESAFAYAIAAAGVVHAVSNACALGKLRACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLSHGVPEHPALPPASPGLQDSWEWGGCSPDVGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQAVMDNMRRKCKCHGTSGSCQLKTCWQVTPEFRAVGALLRNRFHRATLIRPHNRNGGQLEPGPAGAPSPAPGTPGPRRRASPADLVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGPDGCGSMCCGRGHNILRQTRSERCHCRFHWCCFVVCEECRITEWVSVCK.
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For Research Use Only | Not For Clinical Use.
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