Mouse Anti-Rhesus ANPEP Antibody (CBMOAB-35868FYA)
Cat: CBMOAB-35868FYA
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta) |
Clone | MO35868FYA |
Specificity | This antibody binds to Rhesus ANPEP. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Plasma Membrane; Extracellular region or secreted |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. |
Product Overview | Mouse Anti-Rhesus ANPEP Antibody is a mouse antibody against ANPEP. It can be used for ANPEP detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | ANPEP |
UniProt ID | F6VKN1 |
Protein Refseq | The length of the protein is 968 amino acids long. The sequence is show below: MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNAKSSLEASTTPSASATTSNPTLATTLDQSILWNRYRLPNTLKPDSYQVTLRPYLTPDDRGLYIFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDRTELVEPTEYLVVHLRGSLVKDSQYEMDSEFQGELADDLAGFYRSEYMEGDVKKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWIVTEFHTTPKMSTYLLAFIVSEFTYVEKRASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNEVYRVMAVDALASSHPLSTPASEINTPAQISELFDSISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSVQLPTTVHNIMDRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYLWIVPITSIRDGRQQEDYWLMDVRAQNNLFRTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQTDHLAIPVINRAQIINDAFNLASARKVPVTLALTNTLFLIEETEYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYNEINAISTACSNGVPECEEMVSSLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEKEWDFAWEQFRNATLVNEADKLRAALACSNEVWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQSLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEDTGFGSGTRALEQALEKTRANIKWVKENKEVVLQWFTENSK. |
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For Research Use Only | Not For Clinical Use.
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