Mouse Anti-Rhesus APOB Antibody (CBMOAB-36014FYA)


Cat: CBMOAB-36014FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO36014FYA
SpecificityThis antibody binds to Rhesus APOB.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Endoplasmic reticulum; Extracellular region or secreted; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Product OverviewMouse Anti-Rhesus APOB Antibody is a mouse antibody against APOB. It can be used for APOB detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAPOB
UniProt IDF7CEU1
Protein RefseqThe length of the protein is 4555 amino acids long.
The sequence is show below: MGPPRPALLALPALLLLLAGARAEKEMLENVSPVCPRDTTRFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGRALLKKTKNSEEFAAAMSRYELKLVIPEGKQVFLYPEKDEPTHILNIKRGIISALLVPPETEETKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGVSPLALIKGMTHPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNMYGMGVQVTQTLKLEDTPKINSRFFGEGTKKVGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFHKLVTELRGLSEEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPEPSAQQLREIFNMAREQRSRATLYALSHAVNNYHETNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQVTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDEDQEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQLLPREQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYRLYKSVSLPSLDPASAKIEGNLIFDPNNYLPKETMLKTTLTAFGFASADLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKEDKREQDMVNGMMFTVQKLIEDLKSKEVPEARAYLRILGEELGFARLHDLQLLGKLLLTGARTLQGIPQMIGEVIRKGSKNDFFLHYIFIENAFELPTGAGLQLQISSSGVTAPGIKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAHVALKAGQLKFIIPSPKKPVKLLSGSNTLHLVSTTKTEVIPPLIENRQSLSVCKQLFTGLNYCTSSAYSNASSTDSAPYYPLTGDTRLELELRPTGEVEQYSVSATYELQREDRALVDTLKFVTQAEGVKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGRKSYRLTLDIQNKKITEVTLMGHLSCDTKEEGKIKGVISVPRLQAEARSEIIAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSEYPRSLHMYADRLLDHRVPQTDMTFRHVGSKLIVAMNSWLQKASGSLPYTQTLQDHLNSLKELYLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKVEIPLPFGGKSSRDLKMLETVRTPALHFTSVDFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSANVYSNLYNWSASYTGGNTSTDHFSLQARYHMKADSVVDLLSYNVQGSGEATYDHKNTLTLSCGGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKEQHLFVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLISTSDLQSGIIKNTASLKYENYELTLKSDTNGKYENFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGVSTSATTNLKYSPLVLENELNAEIGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKISQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTFNLQLQPYSLVTTLNNDLKYNALDLTNNGKLRLEPLKLHMAGNLKGAYQNNEIKHIYTISSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDISTNYNSDSLHFSNVFHSVMAPFTMTIDTHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLMSRKSISTSLEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELSGRALADLTLLDYPIEVPLLLSEPVNVIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHTINLPFFETLQEYFERNQRTIIVVLENMQRHLKRINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSRAKEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIQFDQYIKDNYDLHDLKIAIANIIDQIIEKLKSLDEHYHIRVNLVKTIHDLHLFIENIDFNKIESSTASWIQNVDTKYQIRIRIQEKLQQLKRHIQNIDIQHLAGKLKQHIEAINVRVLLDQLGTTISFERINDVLEYVKHFVINLIGDFEVAEKINAFRAKVHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDAVKQLDELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDETNNKIRELTQRLNGEIQALELPQKAEALKLFLQETKATVAMYLESLQDTKITLIIDWLQDALSSASLAHMKAKFRETLEDTRDRIYQMDIEQELQRYLSLVGQVYSTLVTFISDWWTLAAKNLTDFAEQYSIQDWAKHVKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKELKDIKIPSRFSTPEFTILNTFHIPSFTIDFVEIKVKIIRTIDQMLNSELQWPVPEVYLRDLKVEDIPLARITLPDFHLPEIAIPEFVIPNLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKINPLALKEFVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNEVIVKINNQLTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLEAGHIAWTSSGKGSWKWACPRFSDEGTHESQISFTIEGPLTSFGLSNKVNSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHSVLTAKGTALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITTSTNNEGNLKVSFPLRLTGKIDFLNNYALFLSPSAQQASWQVSTRFNQYKYNQNFSAGNNKNIMEAHIGINGEANLDFLNIPLTIPEMPLPYTTITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQYKKNTHRHSITNPLAVLYEFTSQNIKSFDKHFEKARNNALGFVTKSYNDAKIKFDKYKAEKSHDELPRTFQIPGYTVPVVNVEVSPFTVEMSAFGYGIPKAVSMPSFTILGSNIRVPSYTLILPSLELPVLQVPRNLKLSLPDFKELCTISHIFIPAMGNITFDFSFKSSVISLNTNAEVFNQSDIVAHLLSSSSSVIDVLQYKLEGTTRLTRKRGLKLATALSLSNKFVEGSHNSTVSLTKKNMEASVATTAKVQIPILRINFKQELNGNTKSKPTVSSSMEFKYDFNSSMLYSTAKGAVDHKLILESLTSYFSIESSTKGDVKGSVLSRDYSGTIASEANTYLNSKSTRSSVKLQGTSKIDDIWNLDVKENFAGEATLQRIYSLWEHSMKNHLKLEGLFFTNGEHTSKATLELSPWEMSAFVQVHASQPNSFLDIPHLGQEVALNANTKNQKIRWKNEVRVHSGSFQNHVELSNDQEKAHLDIAGSLEGHLRFLKNIILPVYGKSLWDFLKLDVTTSIGRRQHLRVSTAFAYTKNPNGYSFSIPVKVLADEFIIPGLKLNDLNSVLVMPTFHVPFTDLQVPSYKLDFREIKIYKKLRTSSFALNLPALPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQLNVSQFTLPKSVSVGSAVLDLNVVANKIADFELPTIIMPEQTIEIPSIKFSVPAGIFIPSFQALTARFEVDSPLYNATWRASLKNKADHVETVLDSTCSSTMQFLEYKLNVVGTHRIEDGMLASKTKGTFAHHDFSAEYEEDGKYKGLREWERKVHLDIKSPAFTDLHLRYQKDKKGISTSAASPAIGTMGMDVDFSKWNIYYSPQSSPDKKLTIFKTELRFRESDEEIQIKVNWEEEAASGLLTSLKDNVPKATGALYDYVNKYHWEHTGLTLREASSKLRRNLQNNAEWVYQGAIRQIDDIDLRFQKAASGTTGTYQKWKDKAQNLYQELLTQEGQTSFQGLKDKVFDGLVRVTQEFHTKVKHLIDSLIDFLNFPRFQFPGKPGTYTGEELCTMFIREVGMVLSQVCLKVHNGSEILFSYFQDLVITLPFELRRHKLIDVISMCREWLKVLSEEAQEVFKDIQSLKTTEVLRNLQDILQFIFQLIEGNIKELKEMKFTHLINYIQDGINTIFNDYIPYVFKLLKENLCLNLHKFNEFIQNELQGASQELQQIHQYIMALREEYFDPSVVGWTVKYYELEEKIVRLIKNLLVALKDFHSEYIVSASDFTSQLSSQVEQFLHRNIQEYLSILTDPDGKGKEKIAELSTTAQEIIKSQAIAMKEIISDYHQQFRYKLQDFSDQLSDYYEKFIAESKRLIDLSIQNYHTFLIYIMELLKKLQSTTVMNSYVKLAPGELTIIL.
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For Research Use Only | Not For Clinical Use.
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