Mouse Anti-Sheep WNT10A Antibody (MO-AB-18252Y)
Cat: MO-AB-18252Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Sheep (Ovis aries) |
Clone | MO18252Y |
Specificity | This antibody binds to Sheep WNT10A. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Extracellular region or secreted |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt''s lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. |
Product Overview | This product is a mouse antibody against WNT10A. It can be used for WNT10A detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Protein Wnt; WNT10A |
UniProt ID | W5QER5 |
Protein Refseq | The length of the protein is 401 amino acids long. The sequence is show below: MGSTHPCPWLRLRPRPQPRPALCALFFLLLLAASVPRSAPNDILGLRLPQEPVLNANTVCLTLPGLSKRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKIPYESPIFSRGFRESAFAYAISAARVVHAVSNACALGKLRACGCDASRRGDEEAFRRKLHRLQLEALQRGKGLSHGVPEHPALPPASPGLQDSWEWGGCSPDVGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQAVMENMRRKCKCHGTSGSCQFKTCWRAAPEFRAVGTALRERLGRAIFIDAHNRNSGAFQPRLRPRRLSGELVYFEKSPDFCERDPAVGSPGTRGRACNTAPGLPGHGAAPAPPTWSTSRSRSERCHCRFHWCCFVVCEECRITEWVSVCK. |
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For Research Use Only | Not For Clinical Use.
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