Mouse Anti-Yeast ATG16 Antibody (CBMOAB-00373CR)


Cat: CBMOAB-00373CR
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast
CloneMO00373CR
SpecificityThis antibody binds to Yeast ATG16.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionStabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruits also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.
Product OverviewMouse Anti-Yeast ATG16 Antibody is a mouse antibody against ATG16. It can be used for ATG16 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAutophagy protein 16; Cytoplasm to vacuole targeting protein 11; SAP18 homolog; ATG16; APG15 APG16 CVT11 SAP18; YMR159C
UniProt IDQ03818
Protein RefseqThe length of the protein is 150 amino acids long. The sequence is show below: MGNFIITERKKAKEERSNPQTDSMDDLLIRRLTDRNDKEAHLNELFQDNSGAIGGNIVSHDDALLNTLAILQKELKSKEQEIRRLKEVIALKNKNTERLNDELISGTIENNVLQQKLSDLKKEHSQLVARWLKKTEKETEAMNSEIDGTK.
For Research Use Only | Not For Clinical Use.
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