Mouse Anti-Zebrafish derl1 Antibody (CBMOAB-63917FYA)


Cat: CBMOAB-63917FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio)
CloneMO63917FYA
SpecificityThis antibody binds to Zebrafish derl1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationEndoplasmic reticulum

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Product OverviewMouse Anti-Zebrafish derl1 Antibody is a mouse antibody against derl1. It can be used for derl1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDerlin 1; derl1
UniProt IDF1Q4W3
Protein RefseqThe length of the protein is 261 amino acids long.
The sequence is show below: MSDIGDWFKNIPFITRYWFAGSIAVPLIGKLGLIGPMYLVLWPEAFFHKFQIWRPITATLYFPVGPGTGFLYLVNLYFLYQYSSRLETGAFDGRPADYMFMLLFNWICIVITGLMMDMQLLMIPLIMSVLYVWAQLNRDTIVSFWFGTRFKACYLPWVILGFNYIIGGSVVNELIGNLVGHLYFFLMFKYPMDLGGRSFLSTPQFLYQMFPNRRGGVSGFGVPPSRRPMPQEQAGGGGGGGGGGGGGGRHNWGQGFRLGDD.
For Research Use Only | Not For Clinical Use.
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