ATP-binding cassette sub-family G member 8, Fragment
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
Mouse Anti-ABCG8 Antibody (CBMOAB-1356FYC) (CAT#: CBMOAB-1356FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Pig (Sus scrofa), Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: ABC transporter G family member 8
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: ATP Binding Cassette Subfamily G Member 8, ATP-Binding Cassette, Sub-Family G (WHITE), Member 8, Sterolin 2, ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (Sterolin 2), ATP-Binding Cassette Sub-Family G Member 8, Gallbladder Disease 4, Sterolin-2, STSL, GBD4