Integrin alpha-L
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Mouse Anti-ITGAL Antibody (CBMOAB-00194FYA) (CAT#: CBMOAB-00194FYA)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa), Cattle (Bos taurus), Goat (Capra hircus), Horse (Equus caballus), Rhesus (Macaca mulatta), Sheep (Ovis aries)
- Application: FC
- Protein: Integrin alpha-L
- Size: 100µg
- Conjugate: None
- Alternative Names: CD11 antigen-like family member A, LFA-1A, antigen CD11A, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte function-associated antigen 1, alpha
For Research Use Only | Not For Clinical Use.
