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Integrin alpha M

Integrin αM (ITGAM) is a protein subunit that can form heterodimeric integrin α-Mbeta-2 (αMβ2) molecules, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM, also known as CR3A, is a cluster of differentiation molecules 11B (CD11B). The second chain of αMβ2 is a common integrin β2 subunit called CD18, so integrin αMβ2 belongs to the β2 subfamily (or leukocyte) integrin.

αMβ2 is expressed on the surface of many white blood cells involved in the innate immune system, including monocytes, granulocytes, macrophages and natural killer cells. It mediates inflammation by regulating the adhesion and migration of leukocytes, and is related to various immune processes such as phagocytosis, cell-mediated cytotoxicity, chemotaxis and cell activation. It participates in the complement system because it has the ability to bind the inactivated complement component 3b (iC3b). The ITGAMα subunit of integrin αMβ2 is directly involved in causing cell adhesion and spreading, but if β2 (CD18) subunit is not present, it cannot mediate cell migration.

Cat# Product Name Host species Species Reactivity Application Size Conjugate Alternative Names Protein
CBMOAB-00016FYA Mouse Anti-Cattle ITGAM Antibody (CBMOAB-00016FYA) Mouse Cattle (Bos taurus) FC 100µg None CD11B Submitted name: Integrin alpha M
CBMOAB-00017FYA Mouse Anti-Cattle ITGAM Antibody (CBMOAB-00017FYA) Mouse Cattle (Bos taurus) FC 100µg None CD11B Submitted name: Integrin alpha M
CBMOAB-00173FYA Mouse Anti-Rabbit ITGAM Antibody (CBMOAB-00173FYA) Mouse Rabbit (Oryctolagus cuniculus) FC 100µg None CD11B Submitted name: Integrin alpha M
MO-AB-03868W Mouse Anti-Rhesus ITGAM Antibody (MO-AB-03868W) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Integrin alpha-M isoform 1, ITGAM Submitted name: Integrin alpha-M isoform 1
MO-AB-14326R Mouse Anti-Cattle ITGAM Antibody (MO-AB-14326R) Mouse Cattle (Bos taurus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP ITGAM protein, Fragment, ITGAM Submitted name: ITGAM protein
MO-AB-14327R Mouse Anti-Cattle ITGAM Antibody (MO-AB-14327R) Mouse Cattle (Bos taurus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Integrin alpha M, ITGAM Submitted name: Integrin alpha M
MO-AB-41893W Mouse Anti-Guinea pig ITGAM Antibody (MO-AB-41893W) Mouse Guinea pig (Cavia porcellus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD antigen CD11b, ITGAM Integrin alpha-M
MO-DKB-00397W Rabbit Anti-ITGAM Antibody (MO-DKB-00397W) Rabbit Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), C. elegans (Caenorhabditis elegans), Chinese Hamster, Primat, Rhesus (Macaca mulatta) WB, SimpleWestern, FC, IF, IHC, IHC-Fr, IHC-P, ISH, DualISH-IHC, Single-CellWestern 100µL NONE Integrin Subunit Alpha M Integrin alpha-M
MOFY-0522-FY38 Mouse Anti-ITGAM Antibody (MOFY-0522-FY38) Mouse Human, Porcine, Rhesus, Cynomolgus, Chimpanzee, Baboon FC, IHC, WB 100Tests Alexa Fluor®488, Alexa Fluor®647, Biotin, NONE, PACBLU, PE, SPRD ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M Integrin alpha M
MOFY-0522-FY47 Rat Anti-ITGAM Antibody (MOFY-0522-FY47) Rat Mouse, Human, Rhesus, Baboon, Rabbit FC 100µg APC, APC/CY7, Biotin, CY5, LE/AF, NONE, PE/CY7, SPRD ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M Integrin alpha M
CBMOAB-81258FYA Mouse Anti-Zebrafish itgam Antibody (CBMOAB-81258FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP itgam, Integrin Subunit Alpha M Submitted name: Integrin, alpha M (complement component 3 receptor 3 subunit)
MO-AB-26742R Mouse Anti-Pig Itgam Antibody (MO-AB-26742R) Mouse Pig (Sus scrofa) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Integrin alpha-M, Itgam Submitted name: Integrin alpha-M
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