Integrin alpha M

Integrin αM (ITGAM) is a protein subunit that can form heterodimeric integrin α-Mbeta-2 (αMβ2) molecules, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM, also known as CR3A, is a cluster of differentiation molecules 11B (CD11B). The second chain of αMβ2 is a common integrin β2 subunit called CD18, so integrin αMβ2 belongs to the β2 subfamily (or leukocyte) integrin.

αMβ2 is expressed on the surface of many white blood cells involved in the innate immune system, including monocytes, granulocytes, macrophages and natural killer cells. It mediates inflammation by regulating the adhesion and migration of leukocytes, and is related to various immune processes such as phagocytosis, cell-mediated cytotoxicity, chemotaxis and cell activation. It participates in the complement system because it has the ability to bind the inactivated complement component 3b (iC3b). The ITGAMα subunit of integrin αMβ2 is directly involved in causing cell adhesion and spreading, but if β2 (CD18) subunit is not present, it cannot mediate cell migration.

  • Mouse Anti-Rabbit ITGAM Antibody (CBMOAB-00173FYA) (CAT#: CBMOAB-00173FYA)

    • Host species: Mouse
    • Species Reactivity: Rabbit (Oryctolagus cuniculus)
    • Application: FC
    • Protein: Submitted name: Integrin alpha M
    • Size: 100µg
    • Conjugate: None
    • Alternative Names: CD11B

  • Mouse Anti-Rhesus ITGAM Antibody (MO-AB-03868W) (CAT#: MO-AB-03868W)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Integrin alpha-M isoform 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Integrin alpha-M isoform 1, ITGAM

  • Mouse Anti-Cattle ITGAM Antibody (MO-AB-14327R) (CAT#: MO-AB-14327R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Submitted name: Integrin alpha M
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Integrin alpha M, ITGAM

  • Mouse Anti-Guinea pig ITGAM Antibody (MO-AB-41893W) (CAT#: MO-AB-41893W)

    • Host species: Mouse
    • Species Reactivity: Guinea pig (Cavia porcellus)
    • Application: WB, ELISA
    • Protein: Integrin alpha-M
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD antigen CD11b, ITGAM

  • Rabbit Anti-ITGAM Antibody (MO-DKB-00397W) (CAT#: MO-DKB-00397W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), C. elegans (Caenorhabditis elegans), Chinese Hamster, Primat, Rhesus (Macaca mulatta)
    • Application: WB, SimpleWestern, FC, IF, IHC, IHC-Fr, IHC-P, ISH, DualISH-IHC, Single-CellWestern
    • Protein: Integrin alpha-M
    • Size: 100µL
    • Conjugate: NONE
    • Alternative Names: Integrin Subunit Alpha M

  • Mouse Anti-ITGAM Antibody (MOFY-0522-FY38) (CAT#: MOFY-0522-FY38)

    • Host species: Mouse
    • Species Reactivity: Human, Porcine, Rhesus, Cynomolgus, Chimpanzee, Baboon
    • Application: FC, IHC, WB
    • Protein: Integrin alpha M
    • Size: 100Tests
    • Conjugate: Alexa Fluor®488, Alexa Fluor®647, Biotin, NONE, PACBLU, PE, SPRD
    • Alternative Names: ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M

  • Rat Anti-ITGAM Antibody (MOFY-0522-FY47) (CAT#: MOFY-0522-FY47)

    • Host species: Rat
    • Species Reactivity: Mouse, Human, Rhesus, Baboon, Rabbit
    • Application: FC
    • Protein: Integrin alpha M
    • Size: 100µg
    • Conjugate: APC, APC/CY7, Biotin, CY5, LE/AF, NONE, PE/CY7, SPRD
    • Alternative Names: ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M

  • Mouse Anti-Zebrafish itgam Antibody (CBMOAB-81258FYA) (CAT#: CBMOAB-81258FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Submitted name: Integrin, alpha M (complement component 3 receptor 3 subunit)
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: itgam, Integrin Subunit Alpha M

  • Mouse Anti-Pig Itgam Antibody (MO-AB-26742R) (CAT#: MO-AB-26742R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: Submitted name: Integrin alpha-M
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Integrin alpha-M, Itgam
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