Mediator of RNA polymerase II transcription subunit 12

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome.

  • Mouse Anti-Arabidopsis MED12 Antibody (CBMOAB-36335FYC) (CAT#: CBMOAB-36335FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Mediator of RNA polymerase II transcription subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Mediator Complex Subunit 12, Thyroid Hormone Receptor-Associated Protein Complex 230 KDa Component, Trinucleotide Repeat-Containing Gene 11 Protein, Activator-Recruited Cofactor 240 KDa Component, OPA-Containing Protein, CAG Repeat Protein 45, TRAP230, TNRC11, ARC240, CAGH45, HOPA, Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog (S. Cerevisiae), Trinucleotide Repeat Containing 11 (THR-Associated Protein, 230 KDa Subunit), Trinucleotide Repeat Containing 11 (THR-Associated Protein, 230kDa Subunit)
  • Mouse Anti-Rhesus MED12 Antibody (CBMOAB-51080FYA) (CAT#: CBMOAB-51080FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Mediator of RNA polymerase II transcription subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Mediator of RNA polymerase II transcription subunit 12, MED12
  • Mouse Anti-Chimpanzee MED12 Antibody (MO-AB-27008W) (CAT#: MO-AB-27008W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Submitted name: Mediator of RNA polymerase II transcription subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Mediator of RNA polymerase II transcription subunit 12, MED12
  • Mouse Anti-Pig MED12 Antibody (MO-AB-27241R) (CAT#: MO-AB-27241R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: Submitted name: Mediator complex subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Mediator of RNA polymerase II transcription subunit 12, MED12
  • Mouse Anti-Marmoset MED12 Antibody (MO-AB-58915W) (CAT#: MO-AB-58915W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: Submitted name: Mediator of RNA polymerase II transcription subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Mediator of RNA polymerase II transcription subunit 12, MED12
  • Mouse Anti-Zebrafish med12 Antibody (CBMOAB-86415FYA) (CAT#: CBMOAB-86415FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Mediator of RNA polymerase II transcription subunit 12
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12, Protein kohtalo, Protein motionless, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, med12, kto mot trap23
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