Severe Acute Respiratory Syndrome Coronavirus 2
Coronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein.
Rat Anti-S1 Antibody (AA 16-677) (CAT#: MO-NAB-00880W)
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- Host species: Rat
- Species Reactivity: SARS-CoV-2 (2019-nCoV)
- Application: ELISA
- Protein: Spike glycoprotein
- Conjugate: NONE
- Alternative Names: Spike glycoprotein, E2, Peplomer protein, Spike protein S1, S