Mouse Anti-ATG7 Antibody (CBMOAB-24522FYC)


Cat: CBMOAB-24522FYC
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-24522FYC Monoclonal A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Maize (Zea mays), Pig (Sus scrofa), Rhesus (Macaca mulatta), Yeast WB, ELISA MO24522FC 100 µg
CBMOAB-02010FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO02010FYA 100 µg
CBMOAB-36505FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO36505FYA 100 µg
CBMOAB-00394CR Monoclonal Yeast WB, ELISA MO00394CR 100 µg
CBMOAB-00756HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO00756HB 100 µg
MO-AB-10488W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO10488W 100 µg
MO-AB-47422W Monoclonal Maize (Zea mays) WB, ELISA MO47422W 100 µg
MO-AB-07758R Monoclonal Cattle (Bos taurus) WB, ELISA MO07758R 100 µg
MO-AB-23919R Monoclonal Pig (Sus scrofa) WB, ELISA MO23919R 100 µg
MO-DKB-0061RA Polyclonal A. thaliana (Arabidopsis thaliana) WB 50 µL

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Maize (Zea mays), Pig (Sus scrofa), Rhesus (Macaca mulatta), Yeast
CloneMO24522FC
SpecificityThis antibody binds to Arabidopsis ATG7.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-Arabidopsis ATG7 Antibody is a mouse antibody against ATG7. It can be used for ATG7 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAutophagy Related 7; Ubiquitin-Activating Enzyme E1-Like Protein; ATG12-Activating Enzyme E1 ATG7; APG7-LIKE; APG7L; HAGP7; ATG7 Autophagy Related 7 Homolog (S. Cerevisiae)
UniProt IDQ94CD5
Protein RefseqThe length of the protein is 697 amino acids long. The sequence is show below: MAEKETPAIILQFAPLNSSVDEGFWHSFSSLKLDKLGIDDSPISITGFYGPCGHPQVSNHLTLLSESLPLDEQSLIASTSHGNRNKCPVPGILYNTNTVESFNKLDKQSLLKAEANKIWEDIQSGKALEDPSVLPRFLVISFADLKKWSFRYWFAFPAFVLDPPVSLIELKPASEYFSSEEAESVSAACNDWRDSDLTTDVPFFLVSVSSDSKASIRHLKDLEACQGDHQKLLFGFYDPCHLPSNPGWPLRNYLALIRSRWNLETVWFFCYRESRGFADLNLSLVGQASITLSSGESAETVPNSVGWELNKGKRVPRSISLANSMDPTRLAVSAVDLNLKLMRWRALPSLNLNVLSSVKCLLLGAGTLGCQVARTLMGWGIRNITFVDYGKVAMSNPVRQSLYNFEDCLGRGEFKAVAAVKSLKQIFPAMETSGVVMAIPMPGHPISSQEEDSVLGDCKRLSELIESHDAVFLLTDTRESRWLPSLLCANANKIAINAALGFDSYMVMRHGAGPTSLSDDMQNLDINKTNTQRLGCYFCNDVVAPQDSMTDRTLDQQCTVTRPGLAPIAGALAVELLVGVLQHPLGINAKGDNSSLSNTGNNDDSPLGILPHQIRGSVSQFSQITLLGQASNSCTACSETVISEYRERGNSFILEAINHPTYLEDLTGLTELKKAANSFNLDWEDDDTDDDDVAVDL.

Reference

Reference1. Wang, P., Sun, X., Wang, N., Jia, X., & Ma, F. (2017). Ectopic expression of an autophagy-associated MdATG7b gene from apple alters growth and tolerance to nutrient stress in Arabidopsis thaliana. Plant Cell, Tissue and Organ Culture (PCTOC), 128, 9-23.
2. Thompson, A. R., Doelling, J. H., Suttangkakul, A., & Vierstra, R. D. (2005). Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant physiology, 138(4), 2097-2110.
See other products for " ATG7 "

Relate Reference Data

Figure 1 Description of the Arabidopsis atg5-1 and atg5-2 mutants. A, Diagram of the Arabidopsis ATG5 gene. Lines indicate introns. Boxes indicate exons, with coding regions in black and the 5' and 3' UTRs in gray. The arrowhead locates the Lys (K-128) that provides the attachment site for ATG12. The locations of the T-DNA in the atg5-1 and atg5-2 mutants are shown.
Reference: Thompson, A. R., Doelling, J. H., Suttangkakul, A., & Vierstra, R. D. (2005). Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant physiology, 138(4), 2097-2110.

For Research Use Only | Not For Clinical Use.
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