Cat: CBMOAB-00192HCB
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO00192HB |
| Specificity | This antibody binds to C. elegans ABL1. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2 weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma Membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. |
| Product Overview | Mouse Anti-C. elegans ABL1 (clone MO00192HB) Antibody (CBMOAB-00192HCB) is a mouse antibody against ABL1. It can be used for ABL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Tyrosine-protein kinase abl-1; EC 2.7.10.2; abl-1 |
| Gene ID | 181261 |
| UniProt ID | P03949 |
| Protein Refseq | The length of the protein is 1224 amino acids long. The sequence is show below: MGHSHSTGKEINDNELFTCEDPVFDQPVASPKSEISSKLAEEIERSKSPLILEVSPRTPDSVQMFRPTFDTFRPPNSDSSTFRGSQSREDLVACSSMNSVNNVHDMNTVSSSSSSSAPLFVALYDFHGVGEEQLSLRKGDQVRILGYNKNNEWCEARLYSTRKNDASNQRRLGEIGWVPSNFIAPYNSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMFITQEVKFRTLGELVHHHSVHADGLICLLMYPASKKDKGRGLFSLSPNAPDEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQKQLKKNNDKKLESDKRRSNVRERSDSKSRHSSHHDRDRDRESLHSRNSNPEIPNRSFIRTDDSVSFFNPSTTSKVTSFRAQGPPFPPPPQQNTKPKLLKSVLNSNARHASEEFERNEQDDVVPLAEKNVRKAVTRLGGTMPKGQRIDAYLDSMRRVDSWKESTDADNEGAGSSSLSRTVSNDSLDTLPLPDSMNSSTYVKMHPASGENVFLRQIRSKLKKRSETPELDHIDSDTADETTKSEKSPFGSLNKSSIKYPIKNAPEFSENHSRVSPVPVPPSRNASVSVRPDSKAEDSSDETTKDVGMWGPKHAVTRKIEIVKNDSYPNVEGELKAKIRNLRHVPKEESNTSSQEDLPLDATDNTNDSIIVIPRDEKAKVRQLVTQKVSPLQHHRPFSLQCPNNSTSSAISHSEHADSSETSSLSGVYEERMKPELPRKRSNGDTKVVPVTWIINGEKEPNGMARTKSLRDITSKFEQLGTASTIESKIEEAVPYREHALEKKGTSKRFSMLEGSNELKHVVPPRKNRNQDESGSIDEEPVSKDMIVSLLKVIQKEFVNLFNLASSEITDEKLQQFVIMADNVQKLHSTCSVYAEQISPHSKFRFKELLSQLEIYNRQIKFSHNPRAKPVDDKLKMAFQDCFDQIMRLVDR. |
See other products for " ABL1 "
| MO-AB-00880W | Mouse Anti-Rhesus ABL1 Antibody (MO-AB-00880W) |
| CBMOAB-64507FYA | Mouse Anti-Zebrafish abl1 Antibody (CBMOAB-64507FYA) |
| MO-AB-50247W | Mouse Anti-Marmoset ABL1 Antibody (MO-AB-50247W) |
| MO-AB-19735W | Mouse Anti-Chimpanzee ABL1 Antibody (MO-AB-19735W) |
| MO-AB-18173W | Mouse Anti-Chimpanzee ABL1 Antibody (MO-AB-18173W) |
| MO-AB-19737W | Mouse Anti-Chimpanzee ABL1 Antibody (MO-AB-19737W) |
| MO-AB-50249W | Mouse Anti-Marmoset ABL1 Antibody (MO-AB-50249W) |
| MO-AB-50246W | Mouse Anti-Marmoset ABL1 Antibody (MO-AB-50246W) |
| MO-AB-00882W | Mouse Anti-Rhesus ABL1 Antibody (MO-AB-00882W) |
| MO-AB-00881W | Mouse Anti-Rhesus ABL1 Antibody (MO-AB-00881W) |
For Research Use Only | Not For Clinical Use.