Mouse Anti-C. elegans HTZ1 Antibody (CBMOAB-05183HCB)


Cat: CBMOAB-05183HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO05183HB
SpecificityThis antibody binds to C. elegans HTZ1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal cells through the repression of transcription factor ceh-22 (PubMed:24346701).
Product OverviewMouse Anti-C. elegans HTZ1 Antibody is a mouse antibody against HTZ1. It can be used for HTZ1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesHistone H2A.V; H2A.F / Z; htz-1
UniProt IDQ27511
Protein RefseqThe length of the protein is 140 amino acids long. The sequence is show below: MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKKGAPVPGKPGAPGQGPQ.
For Research Use Only | Not For Clinical Use.
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