Mouse Anti-C. elegans PABP2 Antibody (CBMOAB-00120HCB)


Cat: CBMOAB-00120HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO00120HB
SpecificityThis antibody binds to C. elegans PABP2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInvolved in the 3''-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (PubMed:10481015). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity (PubMed:10481015). May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, possibly by cooperating with swm which regulates nuclear export of fucosyltransferase FucTA (PubMed:21203496).
Product OverviewMouse Anti-C. elegans PABP2 Antibody is a mouse antibody against PABP2. It can be used for PABP2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein PABP-2; pabp-2
Gene ID172768
UniProt IDQ93233
Protein RefseqThe length of the protein is 205 amino acids long. The sequence is show below: MSDNDIIDDDVLNIEDMTGDDADLSAIEGDLNEIEEEQKKLKAIQNEMVGHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRFSGHPKGFAYVEFTEKEGMQNALAMTDSLLRGRQIKVDPKRTNKPGMSTTNRPPFRGRGGRGRGNVIVKYVYAGGFRPRGRGARRRPGFAPY.
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For Research Use Only | Not For Clinical Use.
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