Mouse Anti-Chicken MCM3 Antibody (MO-AB-02868Y)


Cat: MO-AB-02868Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus)
CloneMO02868Y
SpecificityThis antibody binds to Chicken MCM3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus; Cytoskeleton

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5 / CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a mouse antibody against MCM3. It can be used for MCM3 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesDNA replication licensing factor MCM3; MCM3
UniProt IDF1NFJ0
Protein RefseqThe length of the protein is 812 amino acids long. The sequence is show below: MAAPAGGLDDAELREAQRDYLDFLDDEEDQGVYHGKVRDMISDNQYRLLVNINDLRRRNEKRANRLLSNAFEELIAFQRALKDFVASVDATYAKQYEDFYIGLEGSFGSKHVSPRTLTACFLSCIVCVEGIVTKCSLIRPKVVRSVHYCPATKKTIERRYTDLTSLDAFPSSTVYPTKDEENNPLETEYGLSVYKDHQTISIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGGYTSGTFRTILIACHIKQMSKDARPLYSANDVAKIKRFSKSRSKDIFNQLARSLAPSIHGHEFIKKALLCMLLGGVEKVLENGSRIRGDINILLIGDPSVAKSQLLRYVLGTAPRAVGTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTIAKAGIHARLNSRCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDSEQDREISDHVLRMHRYRNPNEQDGDAMPLGSAVEILATDDPDFAQEEEQELQVYEKHDDLLHGPNRRKEKIVSMEFMRKYIHVAKMIKPVLTQESADYIAEEYSSLRSQNQMNSDIARTSPVTARTLETLIRLSTAHAKARMSKTVDLQDAEAALELVQFAYFKKVLEKEKKRKKQVEDDSETEKEEEEEETQPEKEGRKQRRKKARTEGEEESYDPYDFSDAEQEMPEVQAHTPKTPESSATGEAKKPELADPRLKAFKAALLEVFKSSHAQSVGLKNVMESINRDNPEPFSLAEVKVALAHMQDDNQIMVSDDIIFLI.
For Research Use Only | Not For Clinical Use.
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