DNA replication licensing factor MCM3
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Mouse Anti-MCM3 Antibody (CBMOAB-36305FYC) (CAT#: CBMOAB-36305FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Rice (Oryza), Yeast, Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: DNA replication licensing factor MCM3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: Minichromosome Maintenance Complex Component 3, DNA Polymerase Alpha Holoenzyme-Associated Protein P1, RLF Subunit Beta, P1-MCM3, P102, MCM3 Minichromosome Maintenance Deficient 3 (S. Cerevisiae), Minichromosome Maintenance Deficient (S. Cerevisiae) 3, MCM3 Minichromosome Maintenance Deficient 3, Replication Licensing Factor, Beta Subunit, Minichromosome Maintenance Deficient 3
Mouse Anti-MCM3 Antibody (MO-AB-02868Y) (CAT#: MO-AB-02868Y)
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- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Rice (Oryza), Yeast, Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: DNA replication licensing factor MCM3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: DNA replication licensing factor MCM3, MCM3
