Mouse Anti-D. melanogaster Apc Antibody (CBMOAB-01092FYA)
Cat: CBMOAB-01092FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO01092FYA |
| Specificity | This antibody binds to fruit fly Apc. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Cytosol |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Product Overview | Mouse Anti-D. melanogaster Apc Antibody is a mouse antibody against Apc. It can be used for Apc detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Adenomatous polyposis coli; Apc; D-APC |
| UniProt ID | P91667 |
| Protein Refseq | The length of the protein is 2416 amino acids long. The sequence is show below: MLEPTLTPDLEEGIAELSLEDVDVDSVPERKPHFLDYDAVPPPDYEEGFGASSGEQLKMDKKYERDGEVSDYELAASGYTKKEFTQDDNTLHFTQSAVGLGSGAVGKKPAAKHFLDENPIPPDYMLAQELREMREHRSLDRNFERQSAQQQQLDELPPRNGGGSPASAGRPSRSKEPSYTLSRFLDGDAPAPAPRLPKGAAWTTSFDERYTSSAVEATLGSKVECVYSLLSMLGSNDPLEMAKKFLELSGNAQSCATLRRSGCMPLLVQMMHAPDNDQEVRKCAEQALHNVVHSHPDEKAGRREAKVLRLLDQIVDYCSFLKTLLQSGGEAIADDSDRHPLAAISSLMKVSFDEEHRHAMCELGALHAIPNLVHLDHAVHGPKPEDQCCNSLRRYALMALTNLTFGDENNKALLCGQKQFMEALVAQLDSAPDDLLQVTASVLRNLSWRADSNMKAVLNEIGTVTALALAAMRNRSENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLKIIENAGGILRNVSSHIAVCEPYRQILRQHNCLAILLQQLKSESLTVVSNSCGTLWNLSARSAEDQKFLWDNGAVPMLRSLIHSKHAMISEGSSSALKNLLNFRPAVQNHHQLDPIARSMGLKALPTLEARKAKALQQELGERHTAETCDNLDTGGKLDKER. |
See other products for " APC "
| MO-AB-23780R | Mouse Anti-Pig APC Antibody (MO-AB-23780R) |
| MO-AB-51066W | Mouse Anti-Marmoset APC Antibody (MO-AB-51066W) |
| MO-AB-10482W | Mouse Anti-Chimpanzee APC Antibody (MO-AB-10482W) |
| CBMOAB-66102FYA | Mouse Anti-Zebrafish apc Antibody (CBMOAB-66102FYA) |
| CBMOAB-35985FYA | Mouse Anti-Rhesus APC Antibody (CBMOAB-35985FYA) |
| MO-AB-24099H | Mouse Anti-Rat Apc Antibody (MO-AB-24099H) |
| MO-AB-01089W | Mouse Anti-Rhesus APC Antibody (MO-AB-01089W) |
| MO-AB-07468R | Mouse Anti-Cattle APC Antibody (MO-AB-07468R) |
For Research Use Only | Not For Clinical Use.
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