Mouse Anti-Apc Antibody (CBMOAB-01092FYA)


Cat: CBMOAB-01092FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-01092FYA Monoclonal Fruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) WB, ELISA MO01092FYA 100 µg
CBMOAB-35985FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO35985FYA 100 µg
CBMOAB-66102FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO66102FYA 100 µg
MO-AB-01089W Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO01089W 100 µg
MO-AB-07468R Monoclonal Cattle (Bos taurus) WB, ELISA MO07468R 100 µg
MO-AB-10482W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO10482W 100 µg
MO-AB-23780R Monoclonal Pig (Sus scrofa) WB, ELISA MO23780R 100 µg
MO-AB-24099H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO24099C 100 µg
MO-AB-51066W Monoclonal Marmoset WB, ELISA MO51066W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
CloneMO01092FYA
SpecificityThis antibody binds to fruit fly Apc.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Product OverviewMouse Anti-D. melanogaster Apc Antibody is a mouse antibody against Apc. It can be used for Apc detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAdenomatous polyposis coli; Apc; D-APC
UniProt IDP91667
Protein RefseqThe length of the protein is 2416 amino acids long.
The sequence is show below: MLEPTLTPDLEEGIAELSLEDVDVDSVPERKPHFLDYDAVPPPDYEEGFGASSGEQLKMDKKYERDGEVSDYELAASGYTKKEFTQDDNTLHFTQSAVGLGSGAVGKKPAAKHFLDENPIPPDYMLAQELREMREHRSLDRNFERQSAQQQQLDELPPRNGGGSPASAGRPSRSKEPSYTLSRFLDGDAPAPAPRLPKGAAWTTSFDERYTSSAVEATLGSKVECVYSLLSMLGSNDPLEMAKKFLELSGNAQSCATLRRSGCMPLLVQMMHAPDNDQEVRKCAEQALHNVVHSHPDEKAGRREAKVLRLLDQIVDYCSFLKTLLQSGGEAIADDSDRHPLAAISSLMKVSFDEEHRHAMCELGALHAIPNLVHLDHAVHGPKPEDQCCNSLRRYALMALTNLTFGDENNKALLCGQKQFMEALVAQLDSAPDDLLQVTASVLRNLSWRADSNMKAVLNEIGTVTALALAAMRNRSENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLKIIENAGGILRNVSSHIAVCEPYRQILRQHNCLAILLQQLKSESLTVVSNSCGTLWNLSARSAEDQKFLWDNGAVPMLRSLIHSKHAMISEGSSSALKNLLNFRPAVQNHHQLDPIARSMGLKALPTLEARKAKALQQELGERHTAETCDNLDTGGKLDKER.
For Research Use Only | Not For Clinical Use.
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