Mouse Anti-D. melanogaster Ercc1 Antibody (CBMOAB-16341FYA)
Cat: CBMOAB-16341FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO16341FYA |
| Specificity | This antibody binds to fruit fly Ercc1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. |
| Product Overview | Mouse Anti-D. melanogaster Ercc1 Antibody is a mouse antibody against Ercc1. It can be used for Ercc1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Ercc1; Nucleotide excision repair protein ERCC1; Ercc1 |
| UniProt ID | Q7KMG7 |
| Protein Refseq | The length of the protein is 259 amino acids long. The sequence is show below: MEDFDDDSFNDVLGAMEMPTAAKQPKVDAPAATAVNPAPSNSTEPSGSGRPAPGKPASNPHCVLVHSKQRGNPILKSILNVPLEFRDDIVPDYVVGRTSCVLYLSLKYHNLNPDYICQRLKALGKMYELRVLLVQVDTPEPNNALKSLTRISLLADLTMMLAWNAEEAGKIIETYKQFEKRPPDLIMERVESNPHQKLLAALTNIKPVNKTDAAALLHTFGNLGNIINASEERLSQVMGLGPRKAKKLYKTLQEPFLSK. |
See other products for " ercc1 "
| MO-AB-03356H | Mouse Anti-Frog ercc1 Antibody (MO-AB-03356H) |
| CBMOAB-75264FYA | Mouse Anti-Zebrafish ercc1 Antibody (CBMOAB-75264FYA) |
| MO-AB-15113W | Mouse Anti-Chimpanzee ERCC1 Antibody (MO-AB-15113W) |
| MO-AB-12104R | Mouse Anti-Cattle ERCC1 Antibody (MO-AB-12104R) |
| MO-AB-25703R | Mouse Anti-Pig ERCC1 Antibody (MO-AB-25703R) |
| CBMOAB-41937FYA | Mouse Anti-Rhesus ERCC1 Antibody (CBMOAB-41937FYA) |
| CBMOAB-28485FYC | Mouse Anti-Arabidopsis ERCC1 Antibody (CBMOAB-28485FYC) |
| MO-AB-26883W | Mouse Anti-Chimpanzee ERCC1 Antibody (MO-AB-26883W) |
| CBMOAB-03377HCB | Mouse Anti-C. elegans ERCC1 Antibody (CBMOAB-03377HCB) |
| MO-AB-43132W | Mouse Anti-Hamsters ERCC1 Antibody (MO-AB-43132W) |
For Research Use Only | Not For Clinical Use.
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