Mouse Anti-D. melanogaster Fas Antibody (CBMOAB-16535FYA)


Cat: CBMOAB-16535FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO16535FYA
SpecificityThis antibody binds to fruit fly Fas.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Product OverviewMouse Anti-D. melanogaster Fas Antibody is a mouse antibody against Fas. It can be used for Fas detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFaint sausage; fas
UniProt IDO61674
Protein RefseqThe length of the protein is 822 amino acids long.
The sequence is show below: MRPTFDRRLWILLFIISVQCTTYTQPQNINAKSVQKPKPSERREVISTSSSSSHSWPSISAEPADEVVDHRGGGKPAKCAKNCQKAKAKWAKWRTQLKPHHQAHRAVQHKEARQRQRRETEEDELDAVLRAPSSTSTSTAVATTVQATSSSSSATRSSVINETKAKRPRSTLHLAPEDMQPKPKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEEEDEGPLEPRVLPLRPVPPNPYEAEEMSVVYAEQHSEIKLMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPAHAARWLHGDRVFTPGNQYGTTVLAYAVKDLPTPFCKEARLTYVSMHERVPRTFYFILSTPGGVAEAIFNVNFTKRHRQLSNSIDDDEEEELNRPEQIHFPVFNGSPADGRGWWAVVLALLLVVATTNRH.
See other products for " FAS "
MO-AB-55260WMouse Anti-Marmoset FAS Antibody (MO-AB-55260W)
MO-AB-08050YMouse Anti-Rabbit FAS Antibody (MO-AB-08050Y)
MO-AB-33082HMouse Anti-Nile tilapia FAS Antibody (MO-AB-33082H)
MO-AB-44719WMouse Anti-Horse fas Antibody (MO-AB-44719W)
MO-AB-01855YMouse Anti-Chicken FAS Antibody (MO-AB-01855Y)
MO-AB-19797WMouse Anti-Chimpanzee FAS Antibody (MO-AB-19797W)
CBMOAB-76114FYAMouse Anti-Zebrafish fas Antibody (CBMOAB-76114FYA)
MO-DKB-00114WRabbit Anti-fas Antibody (MO-DKB-00114W)
MO-AB-23203HMouse Anti-Mallard FAS Antibody (MO-AB-23203H)
MO-AB-25767RMouse Anti-Pig FAS Antibody (MO-AB-25767R)
For Research Use Only | Not For Clinical Use.
Online Inquiry