Mouse Anti-Fas Antibody (CBMOAB-16535FYA)


Cat: CBMOAB-16535FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-16535FYA Monoclonal Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Goat (Capra hircus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO16535FYA 100 µg
CBMOAB-42588FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO42588FYA 100 µg
CBMOAB-76114FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO76114FYA 100 µg
MO-AB-01855Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO01855Y 100 µg
MO-AB-05025Y Monoclonal A. aegpti (Aedes aegpti) WB, ELISA MO05025Y 100 µg
MO-AB-08050Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08050Y 100 µg
MO-AB-12374R Monoclonal Cattle (Bos taurus) WB, ELISA MO12374R 100 µg
MO-AB-15222Y Monoclonal Sheep (Ovis aries) WB, ELISA MO15222Y 100 µg
MO-AB-19797W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO19797W 100 µg
MO-AB-23203H Monoclonal Mallard (Anas platyrhynchos) WB, ELISA MO23203C 100 µg
MO-AB-25767R Monoclonal Pig (Sus scrofa) WB, ELISA MO25767R 100 µg
MO-AB-33082H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO33082C 100 µg
MO-AB-37189W Monoclonal Goat (Capra hircus) WB, ELISA MO37189W 100 µg
MO-AB-44719W Monoclonal Horse (Equus caballus) WB, ELISA MO44719W 100 µg
MO-AB-55260W Monoclonal Marmoset WB, ELISA MO55260W 100 µg
MO-DKB-00114W Polyclonal Zebrafish (Danio rerio) ELISA, WB 100 µg
MOFY-0722-FY129 Polyclonal Rhesus WB, IHC, ICC, IP 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Goat (Capra hircus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO16535FYA
SpecificityThis antibody binds to fruit fly Fas.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Product OverviewMouse Anti-D. melanogaster Fas Antibody is a mouse antibody against Fas. It can be used for Fas detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFaint sausage; fas
UniProt IDO61674
Protein RefseqThe length of the protein is 822 amino acids long.
The sequence is show below: MRPTFDRRLWILLFIISVQCTTYTQPQNINAKSVQKPKPSERREVISTSSSSSHSWPSISAEPADEVVDHRGGGKPAKCAKNCQKAKAKWAKWRTQLKPHHQAHRAVQHKEARQRQRRETEEDELDAVLRAPSSTSTSTAVATTVQATSSSSSATRSSVINETKAKRPRSTLHLAPEDMQPKPKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEEEDEGPLEPRVLPLRPVPPNPYEAEEMSVVYAEQHSEIKLMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPAHAARWLHGDRVFTPGNQYGTTVLAYAVKDLPTPFCKEARLTYVSMHERVPRTFYFILSTPGGVAEAIFNVNFTKRHRQLSNSIDDDEEEELNRPEQIHFPVFNGSPADGRGWWAVVLALLLVVATTNRH.
For Research Use Only | Not For Clinical Use.
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