Mouse Anti-Fas Antibody (CBMOAB-16535FYA)
Cat: CBMOAB-16535FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-16535FYA | Monoclonal | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Goat (Capra hircus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) | WB, ELISA | MO16535FYA | 100 µg | ||
CBMOAB-42588FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO42588FYA | 100 µg | ||
CBMOAB-76114FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO76114FYA | 100 µg | ||
MO-AB-01855Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO01855Y | 100 µg | ||
MO-AB-05025Y | Monoclonal | A. aegpti (Aedes aegpti) | WB, ELISA | MO05025Y | 100 µg | ||
MO-AB-08050Y | Monoclonal | Rabbit (Oryctolagus cuniculus) | WB, ELISA | MO08050Y | 100 µg | ||
MO-AB-12374R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO12374R | 100 µg | ||
MO-AB-15222Y | Monoclonal | Sheep (Ovis aries) | WB, ELISA | MO15222Y | 100 µg | ||
MO-AB-19797W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO19797W | 100 µg | ||
MO-AB-23203H | Monoclonal | Mallard (Anas platyrhynchos) | WB, ELISA | MO23203C | 100 µg | ||
MO-AB-25767R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO25767R | 100 µg | ||
MO-AB-33082H | Monoclonal | Nile tilapia (Oreochromis niloticus) | WB, ELISA | MO33082C | 100 µg | ||
MO-AB-37189W | Monoclonal | Goat (Capra hircus) | WB, ELISA | MO37189W | 100 µg | ||
MO-AB-44719W | Monoclonal | Horse (Equus caballus) | WB, ELISA | MO44719W | 100 µg | ||
MO-AB-55260W | Monoclonal | Marmoset | WB, ELISA | MO55260W | 100 µg | ||
MO-DKB-00114W | Polyclonal | Zebrafish (Danio rerio) | ELISA, WB | 100 µg | |||
MOFY-0722-FY129 | Polyclonal | Rhesus | WB, IHC, ICC, IP | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Goat (Capra hircus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) |
Clone | MO16535FYA |
Specificity | This antibody binds to fruit fly Fas. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |
Product Overview | Mouse Anti-D. melanogaster Fas Antibody is a mouse antibody against Fas. It can be used for Fas detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Faint sausage; fas |
UniProt ID | O61674 |
Protein Refseq | The length of the protein is 822 amino acids long. The sequence is show below: MRPTFDRRLWILLFIISVQCTTYTQPQNINAKSVQKPKPSERREVISTSSSSSHSWPSISAEPADEVVDHRGGGKPAKCAKNCQKAKAKWAKWRTQLKPHHQAHRAVQHKEARQRQRRETEEDELDAVLRAPSSTSTSTAVATTVQATSSSSSATRSSVINETKAKRPRSTLHLAPEDMQPKPKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEEEDEGPLEPRVLPLRPVPPNPYEAEEMSVVYAEQHSEIKLMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPAHAARWLHGDRVFTPGNQYGTTVLAYAVKDLPTPFCKEARLTYVSMHERVPRTFYFILSTPGGVAEAIFNVNFTKRHRQLSNSIDDDEEEELNRPEQIHFPVFNGSPADGRGWWAVVLALLLVVATTNRH. |
For Research Use Only | Not For Clinical Use.
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