Mouse Anti-Per Antibody (CBMOAB-27454FYA)

Name: Mouse Anti-Per Antibody (CBMOAB-27454FYA)
SKU: CBMOAB-27454FYA
Rating: 5 (1 reviews)

Cat: CBMOAB-27454FYA

Certificate of Analysis Lookup
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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-27454FYA	Monoclonal	Fruit fly (Drosophila melanogaster), Barrel medic (Medicago truncatula), Silkworm (Bombyx mori)	WB, ELISA	MO27454FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 1224 amino acids long. The sequence is show below: MEGGESTESTHNTKVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQGAGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKLKISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSSVTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNGTNSGTGTGTASSSKGGTAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPGHGIKRGGSHSWEGEANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGSGTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQAAAAAAQAMPLQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPERPLGSQSAYNKSVYTTTPASMTKKVPGAFHSVTTPAQVQRPSSQSASVKTEPGSSAAVSDPCKKEVPDSSPIPSVMGDYNSDPPCSSSNPANNKKYTDSNGNSDDMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSESKIMEHPEEDQTQHGDG.
MO-AB-00464W	Monoclonal	Barrel medic (Medicago truncatula)	WB, ELISA	MO00464W		100 µg	Inquiry
Protein Refseq: The length of the protein is 602 amino acids long. The sequence is show below: MGGTRYNGGHDQSKRFALVGVSSILLVAMVATVADAQQGQPNVQILCESTQYQQTCHQSLAKAPAETAGVKDLIKAAFSATSEELLKHINSSSLIQELGQDKMTKQAMEVCNEVLDYAVDGIHKSVGAVDKFDINKIHEYSYDLKVWLTGTLSHQQTCLDGFANTTTKAGETMARALNTSIQLSSNAIDMVDAVYDLTNAKRRLLSLDNGYPLWVSEGQRRLLAEATVKPNVVVAQDGSGQFKTLTDAIKTVPANNAQNFVIYVKEGVYNETVNVPKDMAFVTIIGDGPAKTKFTGSLNYADGLLPYNTATFGVNGENFMAKDISIENTAGPEKHQAVALRVTADKAIFYNCQIDGYQATLFAESQRQFYRDCSISGTIDMIYGDAFAVFQNCKLIVRKPLEEQQCFVAADGRTKSDSSSGFVFQSCHFTGEPEVAKIDPKIAYLGRPWKSYSKVVIMDSNIDDIFDPEGYMPWMGSAFKDTCTFYEYNNKGPGADTSKRVKWPGVKSISSTEAAAFYPGKFFEIANATDRDTWIVKSGVPYSLAALDATSNQGATPGQGTVTGTGAGAEGPAPAEGPASAGKSSGLVNKGKVKDNTHNFGQ.
MO-AB-70227W	Monoclonal	Silkworm (Bombyx mori)	WB, ELISA	MO70227W		100 µg	Inquiry
Protein Refseq: The length of the protein is 30 amino acids long. The sequence is show below: MDSLENSENTDKISDSAYSNSCSYSQSRRS.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Fruit fly (Drosophila melanogaster), Barrel medic (Medicago truncatula), Silkworm (Bombyx mori)
Clone	MO27454FYA
Specificity	This antibody binds to fruit fly Per.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations; Cytosol

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Essential for biological clock functions. Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms. Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition. Required for binding of cwo to the E box regions in the promoters of target genes of the transcriptional activator Clock, probably by binding to Clock-cycle heterodimers, reducing their affinity for E box binding and allowing cwo to bind instead (PubMed:27814361). (From uniprot, under CC BY 4.0)
Product Overview	Mouse Anti-D. melanogaster Per Antibody is a mouse antibody against Per. It can be used for Per detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Period circadian protein; Protein clock-6; CLK-6; per
UniProt ID	P07663
Protein Refseq	The length of the protein is 1224 amino acids long. The sequence is show below: MEGGESTESTHNTKVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQGAGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKLKISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSSVTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNGTNSGTGTGTASSSKGGTAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPGHGIKRGGSHSWEGEANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGSGTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQAAAAAAQAMPLQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPERPLGSQSAYNKSVYTTTPASMTKKVPGAFHSVTTPAQVQRPSSQSASVKTEPGSSAAVSDPCKKEVPDSSPIPSVMGDYNSDPPCSSSNPANNKKYTDSNGNSDDMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSESKIMEHPEEDQTQHGDG.

For Research Use Only | Not For Clinical Use.

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