Mouse Anti-PAF1 Antibody (MO-AB-17462R)
Cat: MO-AB-17462R
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
MO-AB-17462R | Monoclonal | Cattle (Bos taurus), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Marmoset, Mouse (Mus musculus), Human (Homo sapiens), Rat (Rattus norvegicus), Primate, Frog (Xenopus), Zebrafish (Danio rerio), Rhesus (Macaca mulatta), Rice (Oryza), Yeast | WB, ELISA | MO17462R | 100 µg | ||
CBMOAB-38042FYC | Monoclonal | A. thaliana (Arabidopsis thaliana) | WB, ELISA | MO38042FC | 100 µg | ||
CBMOAB-53757FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO53757FYA | 100 µg | ||
CBMOAB-91264FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO91264FYA | 100 µg | ||
CBMOAB-00055CR | Monoclonal | Yeast | WB, ELISA | MO00055CR | 100 µg | ||
CBMOAB-08123HCB | Monoclonal | C. elegans (Caenorhabditis elegans) | WB, ELISA | MO08123HB | 100 µg | ||
CBMOAB-88463FYB | Monoclonal | Rice (Oryza) | WB, ELISA | MO88463FYB | 100 µg | ||
MO-AB-13098W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO13098W | 100 µg | ||
MO-AB-60906W | Monoclonal | Marmoset | WB, ELISA | MO60906W | 100 µg | ||
MO-DKB-03488W | Polyclonal | Mouse (Mus musculus), Human (Homo sapiens), Rat (Rattus norvegicus), Cattle (Bos taurus), Primate, Frog (Xenopus), Zebrafish (Danio rerio) | WB | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Marmoset, Mouse (Mus musculus), Human (Homo sapiens), Rat (Rattus norvegicus), Primate, Frog (Xenopus), Zebrafish (Danio rerio), Rhesus (Macaca mulatta), Rice (Oryza), Yeast |
Clone | MO17462R |
Specificity | This antibody binds to Cattle PAF1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3''-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of the RAD6/UBC2-BRE1 ubiquitin ligase complex, which ubiquitinates histone H2B to form H2BK123ub1. Also required for the methylation of histone H3 by the COMPASS complex to form H3K4me, by SET2 to form H3K36me, and by DOT1 to form H3K79me. RNA polymerase II associated protein important for transcription of a subset of genes. Required for both positive and negative regulation. Negatively regulates MAK16 expression. Also required for efficient CLN2 transcription in late G1 and may be involved in transcription of galactose-inducible genes. |
Product Overview | This product is a mouse antibody against PAF1. It can be used for PAF1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | RNA polymerase II-associated factor 1 homolog; PAF1 |
UniProt ID | Q2KJ14 |
Protein Refseq | The length of the protein is 532 amino acids long. The sequence is show below: MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGN. |
See other products for " paf1 "
MO-AB-05978H | Mouse Anti-paf1 Antibody (MO-AB-05978H) |
For Research Use Only | Not For Clinical Use.
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