Mouse Anti-Quinidine Antibody (MOFAB-084W)


Cat: MOFAB-084W
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Lot Number

  • Product List
  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MOFAB-084W Monoclonal ELISA WQD11 100 µg
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MOFAB-085W Monoclonal ELISA WQD11 100 µg
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Specifications

Host speciesMouse
CloneWQD11
SpecificityThese antibodies recognize quinidine.
ImmunogenQuinidine conjugated to KLH.
FormatLiquid or Lyophilized
BufferPBS, pH 7.4
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G

Application Information

ApplicationELISA
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionQuinidine is a class I antiarrhythmic drug. Like all other class I antiarrhythmic drugs, quinidine acts primarily by blocking the fast inward sodium current (INa), which results in decreased phase 0 depolarization (decreased Vmax) of the cardiac action potential. Quinidine also blocks the slowly inactivated, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the fast (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI) , ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na/K-ATPase by binding to the same receptor site as digitonin such as ouabain.
Product OverviewThe Quinidine antibody is used as Drug antibodies.
Alternative NamesQuinidine; AB675_7106; Quinidine resistance protein 1; Quinidine
Gene ID28739329
For Research Use Only | Not For Clinical Use.
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