Mouse Anti-Rhesus ACVR2B Antibody (CBMOAB-35057FYA)
Cat: CBMOAB-35057FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta) |
| Clone | MO35057FYA |
| Specificity | This antibody binds to Rhesus ACVR2B. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. |
| Product Overview | Mouse Anti-Rhesus ACVR2B Antibody is a mouse antibody against ACVR2B. It can be used for ACVR2B detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Activin receptor type-2B; ACVR2B |
| UniProt ID | H9Z1Q7 |
| Protein Refseq | The length of the protein is 512 amino acids long. The sequence is show below: MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI. |
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| MO-AB-00039Y | Mouse Anti-Chicken ACVR2B Antibody (MO-AB-00039Y) |
| MO-AB-01220H | Mouse Anti-Frog Acvr2b Antibody (MO-AB-01220H) |
| MO-AB-36667W | Mouse Anti-Goat ACVR2B Antibody (MO-AB-36667W) |
| MO-AB-14083Y | Mouse Anti-Sheep Acvr2b Antibody (MO-AB-14083Y) |
| MO-AB-23519R | Mouse Anti-Pig ACVR2B Antibody (MO-AB-23519R) |
For Research Use Only | Not For Clinical Use.
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