Mouse Anti-Rhesus BLNK Antibody (CBMOAB-37001FYA)


Cat: CBMOAB-37001FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO37001FYA
SpecificityThis antibody binds to Rhesus BLNK.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
Product OverviewMouse Anti-Rhesus BLNK Antibody is a mouse antibody against BLNK. It can be used for BLNK detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBLNK
UniProt IDF7EYN2
Protein RefseqThe length of the protein is 442 amino acids long.
The sequence is show below: RQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYVDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPRVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPERAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPSPAAPSPLPRAGKKPMTPLKTTPVASQQNTSSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQLHQKPIPLPRFTEGGNPTVDGPVPSFSSNSTISEQEAGVLCKPWYAGDCDRKSAEEALHRSNKGDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIKNHQHSPLVLIDSQNNTKDSTRLKYAVKVS.
For Research Use Only | Not For Clinical Use.
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