Mouse Anti-Rhesus CD19 Antibody (CBMOAB-38636FYA)


Cat: CBMOAB-38636FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details
  • Relate Reference Data

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO38636FYA
SpecificityThis antibody binds to Rhesus CD19.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD19 (CD19 Molecule) is a Protein Coding gene. Diseases associated with CD19 include Immunodeficiency, Common Variable, 3 and Common Variable Immunodeficiency. Among its related pathways are RET signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include signal transducer activity, downstream of receptor.
Product OverviewMouse Anti-Rhesus CD19 Antibody is a mouse antibody against CD19. It can be used for CD19 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCD19
UniProt IDF7F486
Protein RefseqThe length of the protein is 557 amino acids long.
The sequence is show below: MPPPCLLFFLLFLTPMEVRPQEPLVVKVEEGDNAVLQCLEGTSDGPTQQLVWCRDSPFEPFLNLSLGLPGMGIRMGPLGIWLLIFNVSNQTGGFYLCQPGLPSEKAWQPGWTVSVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLNSSQLYVWAKDRPEMWEGEPVCGPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVRPKGPKSSLLSLELKDDRPDRDMWVVDTGLLLTRATAQDAGKYYCHRGNWTKSFYLEITARPALWHWLLRIGGWKVPAVTLTYLIFCLCSLVGILQLQRALVLRRKRKRMTDPTRRFFKVTPPPGSGPQNQYGNVLSLPTPTSGLGRAQRWAAGLGGTAPSYGNPSSDVQVDGAVGSRSPPGAGPEEEEGEGYEEPDSEEGSEFYENDSNFGQDQLSQDGSGYENPEDEPLGPEDEDSFSNAESYENEDEELTQPVARTMDFLSPHGSAWDPSREATSLGSQSYEDMRGLLYAAPQLRTIRGQPGPNHEEDADSYENMDNPDGPDPAWGGGGRMGTWSAR.

Reference

Reference1. Sommermeyer, D., Hill, T., Shamah, S. M., Salter, A. I., Chen, Y., Mohler, K. M., & Riddell, S. R. (2017). Fully human CD19-specific chimeric antigen receptors for T-cell therapy. Leukemia, 31(10), 2191-2199.
2. Barese, C. N., Felizardo, T. C., Sellers, S. E., Keyvanfar, K., Di Stasi, A., Metzger, M. E., ... & Dunbar, C. E. (2015). Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques. Stem Cells, 33(1), 91-100.

Figure 1 SFG-iCasp9-2A-ΔCD19 transduction and autologous bone marrow transplantation in rhesus macaques. Marking levels in vivo as assessed by flow cytometry analysis for ΔCD19 expression in peripheral blood leukocytes of the three macaques at different time points after transplantation.

For Research Use Only | Not For Clinical Use.
Online Inquiry