Mouse Anti-Rhesus CD19 Antibody (CBMOAB-38636FYA)
Cat: CBMOAB-38636FYA
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Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta) |
Clone | MO38636FYA |
Specificity | This antibody binds to Rhesus CD19. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma Membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | CD19 (CD19 Molecule) is a Protein Coding gene. Diseases associated with CD19 include Immunodeficiency, Common Variable, 3 and Common Variable Immunodeficiency. Among its related pathways are RET signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include signal transducer activity, downstream of receptor. |
Product Overview | Mouse Anti-Rhesus CD19 Antibody is a mouse antibody against CD19. It can be used for CD19 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | CD19 |
UniProt ID | F7F486 |
Protein Refseq | The length of the protein is 557 amino acids long. The sequence is show below: MPPPCLLFFLLFLTPMEVRPQEPLVVKVEEGDNAVLQCLEGTSDGPTQQLVWCRDSPFEPFLNLSLGLPGMGIRMGPLGIWLLIFNVSNQTGGFYLCQPGLPSEKAWQPGWTVSVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLNSSQLYVWAKDRPEMWEGEPVCGPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVRPKGPKSSLLSLELKDDRPDRDMWVVDTGLLLTRATAQDAGKYYCHRGNWTKSFYLEITARPALWHWLLRIGGWKVPAVTLTYLIFCLCSLVGILQLQRALVLRRKRKRMTDPTRRFFKVTPPPGSGPQNQYGNVLSLPTPTSGLGRAQRWAAGLGGTAPSYGNPSSDVQVDGAVGSRSPPGAGPEEEEGEGYEEPDSEEGSEFYENDSNFGQDQLSQDGSGYENPEDEPLGPEDEDSFSNAESYENEDEELTQPVARTMDFLSPHGSAWDPSREATSLGSQSYEDMRGLLYAAPQLRTIRGQPGPNHEEDADSYENMDNPDGPDPAWGGGGRMGTWSAR. |
Reference
Reference | 1. Sommermeyer, D., Hill, T., Shamah, S. M., Salter, A. I., Chen, Y., Mohler, K. M., & Riddell, S. R. (2017). Fully human CD19-specific chimeric antigen receptors for T-cell therapy. Leukemia, 31(10), 2191-2199. 2. Barese, C. N., Felizardo, T. C., Sellers, S. E., Keyvanfar, K., Di Stasi, A., Metzger, M. E., ... & Dunbar, C. E. (2015). Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques. Stem Cells, 33(1), 91-100. |
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Figure 1 SFG-iCasp9-2A-ΔCD19 transduction and autologous bone marrow transplantation in rhesus macaques. Marking levels in vivo as assessed by flow cytometry analysis for ΔCD19 expression in peripheral blood leukocytes of the three macaques at different time points after transplantation.
For Research Use Only | Not For Clinical Use.
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