Mouse Anti-INPP5E Antibody (CBMOAB-45442FYA)
Cat: CBMOAB-45442FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-45442FYA | Monoclonal | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Zebrafish (Danio rerio) | WB, ELISA | MO45442FYA | 100 µg | ||
| CBMOAB-80921FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO80921FYA | 100 µg | ||
| MO-AB-02729W | Monoclonal | Fruit fly (Drosophila melanogaster) | WB, ELISA | MO02729W | 100 µg | ||
| MO-AB-21894W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO21894W | 100 µg | ||
| MO-AB-57297W | Monoclonal | Marmoset | WB, ELISA | MO57297W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Zebrafish (Danio rerio) |
| Clone | MO45442FYA |
| Specificity | This antibody binds to Rhesus INPP5E. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Golgi apparatus; Cytoskeleton |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. (From NCBI) |
| Product Overview | Mouse Anti-Rhesus INPP5E Antibody is a mouse antibody against INPP5E. It can be used for INPP5E detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | 72 kDa inositol polyphosphate 5-phosphatase; INPP5E |
| UniProt ID | I2CU50 |
| Protein Refseq | The length of the protein is 644 amino acids long. The sequence is show below: MPSKAESLRPSEPAPQPPEGRTLQGQLPGAPLAPRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPVTPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLGSERGSPSSGGNPLSGVASSSPNLLHRNAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRYVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALALPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTAVDTLLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS. |
For Research Use Only | Not For Clinical Use.
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