AibGenesis™ Mouse Anti-PDE6B Antibody (CBMOAB-54133FYA)


Cat: CBMOAB-54133FYA

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-54133FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Zebrafish (Danio rerio) WB, ELISA MO54133FYA 100 µg
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CBMOAB-92013FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO92013FYA 100 µg
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MO-AB-03368Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO03368Y 100 µg
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MO-AB-09828W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO09828W 100 µg
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MO-AB-17683R Monoclonal Cattle (Bos taurus) WB, ELISA MO17683R 100 µg
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MO-AB-26993W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO26993W 100 µg
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MO-AB-32648W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO32648W 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Zebrafish (Danio rerio)
CloneMO54133FYA
SpecificityThis antibody binds to Rhesus PDE6B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionPhoton absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. (From NCBI)
Product OverviewMouse Anti-Rhesus PDE6B Antibody is a mouse antibody against PDE6B. It can be used for PDE6B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPDE6B
UniProt IDF7GPA8
Protein RefseqThe length of the protein is 856 amino acids long.
The sequence is show below: MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDRCPPDCNSFRELCQVEESEALLELVQDMQENINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVKDVAEQCPHFSSFADELTDYKTKNILATPIMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLDLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWPVLMGESQPYSGPRTPDGRELGHSPLHTHVQPGLVPLTPAHTTPPADHWALASGLPSYVAESGFVSPVLSGAPTALPSLGEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTHDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPHVDQNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKGVGRGHTKQEGTNRAVGTEICNGGPAPKSSTCCIL.
For Research Use Only | Not For Clinical Use.
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